EVA1A inhibits GBM cell proliferation by inducing autophagy and apoptosis
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2017.02.003
Abstract: ABSTRACT Eva‐1 homolog A (EVA1A) is a novel lysosome and endoplasmic reticulum‐associated protein involved in autophagy and apoptosis. In this study, we constructed a recombinant adenovirus 5‐EVA1A vector (Ad5‐EVA1A) to overexpress EVA1A in glioblastoma (GBM)… read more here.
Keywords: autophagy apoptosis; cell; eva1a; gbm cell ... See more keywords
CSIG-20. EFFECT OF TUMOR-TREATING FIELDS (TTFIELDS) ON EGFR PHOSPHORYLATION IN GBM CELL LINES
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.190
Abstract: Glioblastoma (GBM) is the most common high grade and most devastating brain tumor among adults. About 50% of GBM express EGFR (epidermal growth factor receptor) and from these another 50% the mutated form EGFRvIII which… read more here.
Keywords: gbm cell; fluorescence; gbm; cell lines ... See more keywords
HOXA-AS2 enhances GBM cell malignancy by suppressing miR-2116-3p thereby upregulating SERPINA3
Sign Up to like & getrecommendations! Published in 2022 at "BMC Cancer"
DOI: 10.1186/s12885-022-09462-y
Abstract: Background Glioblastoma (GBM) is malignant, demanding more attention to the improvement of the diagnosis and therapy. LncRNAs have been implicated in the malignancy of GBM cells. Methods HOXA-AS2, miR-2116-3p and SERPINA3 expression levels in GBM… read more here.
Keywords: mir 2116; gbm cell; gbm; hoxa as2 ... See more keywords
Anticancer Properties of the Antipsychotic Drug Chlorpromazine and Its Synergism With Temozolomide in Restraining Human Glioblastoma Proliferation In Vitro
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.635472
Abstract: The extremely poor prognosis of patients affected by glioblastoma (GBM, grade IV glioma) prompts the search for new and more effective therapies. In this regard, drug repurposing or repositioning can represent a safe, swift, and… read more here.
Keywords: gbm cell; gbm; cell lines; drug ... See more keywords
Monocarboxylate Transporter 4 Regulates Glioblastoma Motility and Monocyte Binding Ability
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12020380
Abstract: Glioblastoma (GBM) is characterized by severe hypoxic and acidic stress in an abnormal microenvironment. Monocarboxylate transporter (MCT)4, a pH-regulating protein, plays an important role in pH homeostasis of the glycolytic metabolic pathways in cancer cells.… read more here.
Keywords: gbm; monocarboxylate transporter; motility monocyte; gbm cell ... See more keywords
Glucose and Inositol Transporters, SLC5A1 and SLC5A3, in Glioblastoma Cell Migration
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14235794
Abstract: Simple Summary Cell migration is the main obstacle to the treatment of highly invasive brain cancer glioblastoma multiforme (GBM). We investigated in vitro the potential role of two solute carrier proteins (SLCs), SLC5A1 and SLC5A3,… read more here.
Keywords: cell; slc5a1 slc5a3; migration; gbm cell ... See more keywords
Genome Editing Using Cas9 Ribonucleoprotein Is Effective for Introducing PDGFRA Variant in Cultured Human Glioblastoma Cell Lines
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010500
Abstract: Many variants of uncertain significance (VUS) have been detected in clinical cancer cases using next-generation sequencing-based cancer gene panel analysis. One strategy for the elucidation of VUS is the functional analysis of cultured cancer cell… read more here.
Keywords: genome editing; cell; human glioblastoma; gbm cell ... See more keywords