Hydrogel matrix presence and composition influence drug responses of encapsulated glioblastoma spheroids.
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DOI: 10.1016/j.actbio.2021.05.005
Abstract: Glioblastoma multiforme (GBM) is the most aggressive brain tumor with median patient survival of 12-15 months. To facilitate treatment development, bioengineered GBM models that adequately recapitulate the in vivo tumor microenvironment are needed. Matrix-encapsulated multicellular… read more here.
Keywords: gbm spheroid; drug responses; hydrogel matrix; matrix ... See more keywords