SARS-CoV-2 evolution influences GBP and IFITM sensitivity
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DOI: 10.1073/pnas.2212577120
Abstract: Significance GBPs and IFITMs are potent innate immune restriction factors that can inhibit viral infectivity. Specifically, GBPs perturb furin-mediated processing of viral envelope proteins, targeting viruses that rely on proteolytic processing for optimal infectivity. Here,… read more here.
Keywords: gbp ifitm; influences gbp; evolution influences; cov evolution ... See more keywords