GBP2 serves as a novel prognostic biomarker and potential immune microenvironment indicator in renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23447
Abstract: Since the application of immune checkpoint therapy (ICT) has gradually become a new strategy for clear cell renal cell carcinoma (ccRCC) treatment, biomarkers that predict the individual response to ICT is needed. This study aimed… read more here.
Keywords: gbp2 expression; ccrcc; cell; indicator ... See more keywords
GBP2 enhances glioblastoma invasion through Stat3/fibronectin pathway
Sign Up to like & getrecommendations! Published in 2020 at "Oncogene"
DOI: 10.1038/s41388-020-1348-7
Abstract: Guanylate-binding protein 2 (GBP2) is an interferon-inducible large GTPase which is crucial to the protective immunity against microorganisms. However, its biological function in cancer remains largely unknown. Glioblastoma multiforme (GBM) is the most common and… read more here.
Keywords: gbp2; gbp2 expression; invasion; stat3 ... See more keywords