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   Articles with "gc1qr" as a keyword



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The role of the globular heads of the C1q receptor in paclitaxel-induced human ovarian cancer cells apoptosis by a mitochondria-dependent pathway

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recommendations! Published in 2017 at "Anti-Cancer Drugs"

DOI: 10.1097/cad.0000000000000567

Abstract: As a mitochondrial membrane protein, globular C1q receptor (gC1qR) can mediate a variety of biological responses. Our study aims to investigate the role of gC1qR in paclitaxel-induced apoptosis of human ovarian cancer cells and to… read more here.

Keywords: human ovarian; gc1qr; ovarian cancer; cancer cells ... See more keywords
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gC1qR/C1qBP/HABP-1: Structural Analysis of the Trimeric Core Region, Interactions With a Novel Panel of Monoclonal Antibodies, and Their Influence on Binding to FXII

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recommendations! Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.887742

Abstract: The protein gC1qR/C1qBP/HABP-1 plays an essential role in mitochondrial biogenesis, but becomes localized at the cellular surface in numerous pathophysiological states. When this occurs on endothelial cells, surface-exposed gC1qR activates the classical pathway of complement.… read more here.

Keywords: gc1qr c1qbp; gc1qr; panel monoclonal; binding fxii ... See more keywords
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gC1qR: A New Target for Cancer Immunotherapy

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recommendations! Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1095943

Abstract: Although breakthroughs in cancer treatment have been achieved, immunotherapy yields only modest benefits in most patients. There is still a gap in clarifying the immune evasiveness and immune-resistance mechanisms. Identifying other candidate targets for cancer… read more here.

Keywords: gc1qr; new target; cancer immunotherapy; cancer ... See more keywords
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Computational Insights into the Interaction between Cytoadherence Receptor gC1qR and the DBLβ12 Domain of a Plasmodium falciparum PfEMP1 Ligand

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recommendations! Published in 2021 at "Life"

DOI: 10.3390/life11090993

Abstract: Human receptor gC1qR is a 32 kD protein that mediates the cytoadherence of Plasmodium falciparum-infected erythrocytes (IEs) to human brain microvascular endothelial cells (HBMEC) and platelets. The cytoadherence of IEs to gC1qR has been associated… read more here.

Keywords: dbl domain; gc1qr; receptor gc1qr; cytoadherence ... See more keywords