Lipopolysaccharide-Elicited Systemic Inflammation Induces Selective Vulnerability of Cerebral Cortex and Striatum of Developing Glutaryl-CoA Dehydrogenase Deficient (Gcdh-/-) Mice to Oxidative Stress.
Sign Up to like & getrecommendations! Published in 2020 at "Neurotoxicity research"
DOI: 10.1007/s12640-020-00291-0
Abstract: We investigated redox homeostasis in cerebral and peripheral tissues of wild type (WT) and glutaryl-CoA dehydrogenase knockout mice (Gcdh-/-) submitted to inflammation induced by lipopolysaccharide (LPS) since patients with glutaric aciduria type I (GA I)… read more here.
Keywords: cerebral cortex; lys; mice; gcdh mice ... See more keywords