Sign Up to like & get
recommendations!
0
Published in 2017 at "Acta Diabetologica"
DOI: 10.1007/s00592-017-1021-y
Abstract: AbstractAimsOur aim was to detect the frequency of glucokinase (GCK) gene mutations in a cohort of patients with impaired fasting glucose and to describe the clinical manifestations of identified variants. We also aimed at predicting…
read more here.
Keywords:
patients impaired;
glucokinase;
impaired fasting;
fasting glucose ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2020 at "Biophysical journal"
DOI: 10.1016/j.bpj.2019.12.036
Abstract: Human glucokinase (GCK) is the prototypic example of an emerging class of proteins with allosteric-like behavior that originates from intrinsic polypeptide dynamics. High-resolution NMR investigations of GCK have elucidated millisecond-timescale dynamics underlying allostery. In contrast,…
read more here.
Keywords:
heterogeneity;
timescale dynamics;
nanosecond timescale;
cooperativity ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2018 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00612-17
Abstract: ABSTRACT To understand how ciliopathies such as polycystic kidney disease or Bardet-Biedl syndrome develop, we need to understand the basic molecular mechanisms underlying cilium development. Cilium growth depends on the presence of functional intraflagellar transport…
read more here.
Keywords:
pkg gck;
kinases pkg;
kinase;
intraflagellar transport ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-117557
Abstract: Introduction: Germinal Center Kinase (GCK) is an essential regulator of stress-activated MAPK core signaling pathways. Recent studies revealing the role of GCK in tumorigenesis and cancer progression have generated increasing interest in validating GCK as…
read more here.
Keywords:
inhibition;
mapk cascade;
cell;
myc ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2021 at "Biodiversitas"
DOI: 10.13057/biodiv/d220227
Abstract: Abstract. Sari DN, Nasrullah H, Ekasari J, Suprayudi MA, Alimuddin A. 2021. Sequence and expression analysis of glucokinase mRNA from herbivorous Giant gourami (Osphronemus goramy). Biodiversitas 22: 741-750. Glucokinase (GCK) is one of the enzymes…
read more here.
Keywords:
sequence expression;
giant gourami;
gck;
gourami ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22020918
Abstract: Maturity-onset diabetes of the young (MODY) type 2 is caused by heterozygous inactivating mutations in the gene encoding glucokinase (GCK), a pivotal enzyme for glucose homeostasis. In the pancreas GCK regulates insulin secretion, while in…
read more here.
Keywords:
drosophila gck;
genomic instability;
mody;
gck ... See more keywords