GCN2 phosphorylates HIV-1 integrase and decreases HIV-1 replication by limiting viral integration
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DOI: 10.1038/s41598-017-02276-0
Abstract: GCN2 is a serine/threonine kinase involved in cellular stress response related to amino acid starvation. Previously, we showed that GCN2 interacts with HIV-1 integrase and is activated during HIV-1 infection. Herein, we identified HIV-1 integrase… read more here.
Keywords: integrase; integration; gcn2; gcn2 phosphorylates ... See more keywords