GCRV 096 VP6 protein and its impacts on GCRV replication with different genotypes in CIK cells
Sign Up to like & getrecommendations! Published in 2018 at "Aquaculture and Fisheries"
DOI: 10.1016/j.aaf.2018.07.005
Abstract: Abstract Grass carp reovirus (GCRV) is the causative agent of grass carp hemorrhagic disease, which has detrimental effects on the grass carp aquaculture industry. There are four known genotypes of GCRV and strains of different… read more here.
Keywords: protein; gcrv; vp6 protein; gcrv 096 ... See more keywords
Molecular detection of genotype II grass carp reovirus based on nucleic acid sequence-based amplification combined with enzyme-linked immunosorbent assay (NASBA-ELISA).
Sign Up to like & getrecommendations! Published in 2017 at "Journal of virological methods"
DOI: 10.1016/j.jviromet.2017.02.001
Abstract: Grass carp reovirus (GCRV) is the causative agent of the grass carp hemorrhagic disease that has resulted in severe economic losses in the grass carp (Ctenopharyngodon idella) farming industry in China. Early diagnosis and vaccine… read more here.
Keywords: grass; gcrv; nasba elisa; grass carp ... See more keywords
Hsp90 Regulates GCRV-II Proliferation by Interacting with VP35 as Its Receptor and Chaperone
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.01175-22
Abstract: Identification of viral receptors has always been the research hot spot in virus research field as receptor functions at the first stage of viral infection, which can be designed as efficient antiviral drug targets. GCRV-II,… read more here.
Keywords: gcrv; hsp90; gcrv proliferation; grass carp ... See more keywords
GCRV-II invades monocytes/macrophages and induces macrophage polarization and apoptosis in tissues to facilitate viral replication and dissemination
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Virology"
DOI: 10.1128/jvi.01469-23
Abstract: ABSTRACT Grass carp reovirus (GCRV), particularly the highly prevalent type II GCRV (GCRV-II), causes huge losses in the aquaculture industry. However, little is known about the mechanisms by which GCRV-II invades grass carp and further… read more here.
Keywords: dissemination; monocytes macrophages; gcrv; grass carp ... See more keywords
Grass Carp Reovirus Induces Formation of Lipid Droplets as Sites for Its Replication and Assembly
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.02297-22
Abstract: Grass carp reovirus (GCRV) is the most virulent pathogen in the genus Aquareovirus, which belongs to the family Reoviridae. GCRV-induced hemorrhagic disease is a major threat to the grass carp aquaculture industry. ABSTRACT Grass carp… read more here.
Keywords: gcrv; replication assembly; grass carp; grass ... See more keywords
An Aquareovirus Exploits Membrane-Anchored HSP70 To Promote Viral Entry
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.04055-22
Abstract: The seasonality of viral diseases in ectotherms is a prevailing phenomenon in the aquatic environment, which causes huge economic losses every year worldwide and hinders sustainable development of the aquaculture industry. Nevertheless, our understanding of… read more here.
Keywords: temperature dependent; gcrv; entry; viral diseases ... See more keywords
Prediction of GCRV virus-host protein interactome based on structural motif-domain interactions
Sign Up to like & getrecommendations! Published in 2017 at "BMC Bioinformatics"
DOI: 10.1186/s12859-017-1500-8
Abstract: BackgroundGrass carp hemorrhagic disease, caused by grass carp reovirus (GCRV), is the most fatal causative agent in grass carp aquaculture. Protein-protein interactions between virus and host are one avenue through which GCRV can trigger infection… read more here.
Keywords: protein; gcrv; motif domain; host ... See more keywords
Sialic acid serves as a functional receptor for grass carp reovirus
Sign Up to like & getrecommendations! Published in 2025 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1013481
Abstract: Grass carp reovirus (GCRV) causes hemorrhagic disease and substantial economic losses in the aquaculture of grass carp (Ctenopharyngodon idella), a commercially important fish species in China. Although viral entry depends on interactions between viral proteins… read more here.
Keywords: gcrv; receptor; grass carp; carp reovirus ... See more keywords
Bid-deficient fish delay grass carp reovirus (GCRV) replication and attenuate GCRV-triggered apoptosis.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19460
Abstract: Bid, BH3-interacting domain death agonist, is a pro-apoptotic BH3-only member of Bcl-2 family, playing an important role in apoptosis. In the study, Bid genes from grass carp (Ctenopharyngodon idellus) and rare minnow (Gobiocypris rarus), named… read more here.
Keywords: apoptosis; gcrv; grass carp; rare minnow ... See more keywords
Analysis of GCRV Pathogenesis and Therapeutic Measures Through Proteomic and Metabolomic Investigations in GCRV-Infected Tissues of Grass Carp (Ctenopharyngodon idella)
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms252111852
Abstract: Hemorrhagic disease caused by grass carp reovirus (GCRV) infection is a major problem affecting the grass carp aquaculture industry. Therefore, inhibiting the spread of GCRV infection is of great economic significance. Herein, we sequenced five… read more here.
Keywords: gcrv infection; analysis; gcrv; grass carp ... See more keywords
Isolation, Identification, and Genomic Analysis of a Novel Reovirus from Healthy Grass Carp and Its Dynamic Proliferation In Vitro and In Vivo
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13040690
Abstract: A new grass carp reovirus (GCRV), healthy grass carp reovirus (HGCRV), was isolated from grass carp in 2019. Its complete genome sequence was determined and contained 11 dsRNAs with a total size of 23,688 bp… read more here.
Keywords: gcrv; analysis; reovirus; grass carp ... See more keywords