pH Switchable Nanoplatform for In Vivo Persistent Luminescence Imaging and Precise Photothermal Therapy of Bacterial Infection
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201909042
Abstract: Photothermal therapy (PTT) is one of the most promising approaches to combat multidrug‐resistant bacteria with less potential to induce resistance and systemic toxicity. However, uncontrollable distribution of photothermal agents leads to lethal temperatures for normal… read more here.
Keywords: bacterial infection; luminescence; gcs; persistent luminescence ... See more keywords
Timing Matters: Lessons From Perinatal Neurogenesis in the Olfactory Bulb
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.70045
Abstract: In the olfactory bulb (OB), odorant receptor‐specific input converges into glomeruli. Subsequently, the coding of odor information is fine‐tuned by local synaptic circuits within the glomeruli and the deeper external plexiform layer (EPL) in the… read more here.
Keywords: olfactory bulb; neurogenesis; timing matters; gcs ... See more keywords
3,3′,4,4′,5‐Pentachlorobiphenyl influences mitochondrial apoptosis pathway in granulosa cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28801
Abstract: 3,3′,4,4′,5‐Polychlorinated biphenyl (PCB126) is a persistent organic environmental pollutant which can affect various biological activities of organisms, such as immunity, neurological function, and reproduction. In our study, we aimed to investigate the effects of PCB126… read more here.
Keywords: granulosa cells; mitochondrial apoptosis; apoptosis; gcs ... See more keywords
Up‐Regulation of miR‐30b‐3p by Krüppel‐Like Factor 5 Induces the Apoptosis and Oxidative Stress in Sow Ovarian Granulosa Cells Through Inhibiting SMAD3 and SOD2
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.70103
Abstract: MicroRNAs (miRNAs) have been demonstrated to be involved in various cellular biological processes. However, their impacts on apoptosis and oxidative stress in ovarian granulosa cells (GC) remain largely unknown. Here, we identified that miR‐30b was… read more here.
Keywords: sow; oxidative stress; mir 30b; gcs ... See more keywords
Clinical and laboratory genetic counselor attitudes on the reporting of variants of uncertain significance for multigene cancer panels.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of genetic counseling"
DOI: 10.1002/jgc4.1680
Abstract: Research suggests variants of uncertain significance (VUSs) present a variety of challenges for genetic counselors (GCs), nongenetics clinicians, and patients. Multigene cancer panels reveal more VUSs than single gene testing as a result of the… read more here.
Keywords: clinical cancer; vuss; gcs; laboratory gcs ... See more keywords
Interpreting traumatic brain injury severity: analysis of the correlation between Glasgow coma scale and abbreviated injury scale
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Trauma and Emergency Surgery"
DOI: 10.1007/s00068-025-02909-4
Abstract: Both the Glasgow Coma Scale (GCS) and Abbreviated Injury Scale (AIS) for head injuries quantify traumatic brain injury (TBI) severity. The GCS is based on brain physiology of consciousness, whereas the AIS is an anatomical… read more here.
Keywords: brain; correlation; gcs; scale ... See more keywords
Follicular factors determining granulosa cell number and developmental competence of porcine oocytes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-018-1247-9
Abstract: PurposeGranulosa cell (GC) number in follicles is a simple characteristic of follicles. The present study examined the hypothesis that follicular fluid (FF) determines GC number and oocyte developmental ability and revealed the molecular background determining… read more here.
Keywords: granulosa cell; number gcs; cell number; gcs ... See more keywords
Upregulation of PD-L1 contributes to improving the apoptosis of granulosa cells via the PI3K/AKT pathway in PCOS
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-024-03327-y
Abstract: Polycystic ovary syndrome (PCOS) is a leading cause of anovulatory infertility and closely correlated with apoptosis in ovarian granulosa cells (GCs). Programmed cell death protein-1/programmed cell death ligand-1 (PD-1/PD-L1) pathway plays an important role throughout… read more here.
Keywords: gcs; pcos; pathway; pi3k akt ... See more keywords
Acidity-triggered charge-convertible nanoparticles that can cause bacterium-specific aggregation in situ to enhance photothermal ablation of focal infection.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2016.11.045
Abstract: Focal infections that are caused by antibiotic-resistant bacteria are becoming an ever-growing challenge to human health. To address this challenge, a pH-responsive amphiphilic polymer of polyaniline-conjugated glycol chitosan (PANI-GCS) that can self-assemble into nanoparticles (NPs)… read more here.
Keywords: pani gcs; gcs; bacterium specific; gcs nps ... See more keywords
Two-Year Follow-up Study of Membranous Nephropathy Treated With Tacrolimus and Corticosteroids Versus Cyclical Corticosteroids and Cyclophosphamide
Sign Up to like & getrecommendations! Published in 2017 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2017.02.004
Abstract: Introduction Both cCTX/GCs and CNIs are recommended as first-line agents in the management of PMN. The present study is an extended report of patients randomized to receive TAC/GCs or cCTX/GCs at 2 years post randomization.… read more here.
Keywords: gcs; cctx gcs; tac gcs; gcs cctx ... See more keywords
SAT-112 CLINICAL TRIAL OF VENGLUSTAT, A GLUCOSYLCERAMIDE SYNTHASE (GCS) INHIBITOR, IS SUPPORTED BY PRECLINICAL AND PHASE 1 STUDY DATA
Sign Up to like & getrecommendations! Published in 2019 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2019.05.140
Abstract: results In three mouse models of PKD, treatment with a GCS inhibitor resulted in decreased kidney and plasma levels of glucosylceramide (GL-1) and reduced formation of kidney cysts compared with untreated controls. Analysis of kidney… read more here.
Keywords: gcs; venglustat; gcs inhibitor; kidney ... See more keywords