Increased levels of XPA might be the basis of cisplatin resistance in germ cell tumours
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DOI: 10.1186/s12885-019-6496-1
Abstract: BackgroundGerm cell tumours (GCTs) represent a highly curable malignity as they respond well to cisplatin (CDDP)-based chemotherapy. Nevertheless, a small proportion of GCT patients relapse or do not respond to therapy. As this might be… read more here.
Keywords: xpa; gct patients; expression; cell ... See more keywords
Are Changes in the Percentage of Specific Leukocyte Subpopulations Associated with Endogenous DNA Damage Levels in Testicular Cancer Patients?
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DOI: 10.3390/ijms22158281
Abstract: Chemoresistance of germ cell tumors (GCTs) represents an intensively studied property of GCTs that is the result of a complicated multifactorial process. One of the driving factors in this process is the tumor microenvironment (TME).… read more here.
Keywords: dna damage; endogenous dna; gct patients; damage ... See more keywords