Articles with "gcv" as a keyword



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Synergistic inhibitory effect of resveratrol and TK/GCV therapy on melanoma cells

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Published in 2020 at "Journal of Cancer Research and Clinical Oncology"

DOI: 10.1007/s00432-020-03203-z

Abstract: Purpose To investigate the synergistic effect of resveratrol on the bystander effect of TK/GCV suicide gene system in melanoma cells. Methods The effect of resveratrol on the growth of B16 cells and the synergistic effect… read more here.

Keywords: resveratrol; effect resveratrol; effect; melanoma cells ... See more keywords

1584. Development and Dynamics of Cytomegalovirus UL97 Ganciclovir Resistance Mutations in Transplant Recipients Detected by Next-generation Sequencing

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Published in 2018 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofy210.1412

Abstract: Abstract Background (Val)ganciclovir resistance mutations (GRMs) in CMV UL97 (UL97-GCV-R) complicate prophylaxis and therapy of solid-organ transplant (SOT) and hematopoietic (stem) cell transplant (HCT) recipients, but data on prevalence and dynamics are scarce. We investigated… read more here.

Keywords: ganciclovir resistance; ul97 gcv; transplant recipients; resistance mutations ... See more keywords

Suicide Gene Therapy Against Malignant Gliomas by the Local Delivery of Genetically Engineered Umbilical Cord Mesenchymal Stem Cells as Cellular Vehicles.

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Published in 2019 at "Current gene therapy"

DOI: 10.2174/1566523219666191028103703

Abstract: BACKGROUND Glioblastoma (GBM) is a malignant tumor that is difficult to eliminate, and new therapies are thus strongly desired. Mesenchymal stem cells (MSCs) have the ability to locate to injured tissues, inflammation sites and tumors… read more here.

Keywords: tumor; effect; stem cells; gcv ... See more keywords

Microneedle-Array-Mediated Transdermal Delivery of GCV-Functionalized Zeolitic Imidazolate Framework-8 Nanoparticles for KSHV Treatment

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Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms252312946

Abstract: Kaposi’s sarcoma-associated herpesvirus (KSHV) is a variety of the human gamma-herpesvirus that often leads to the occurrence of malignant tumors. In addition, the occurrence of Kaposi’s sarcoma is a major cause of death among AIDS… read more here.

Keywords: framework; array mediated; delivery; gcv ... See more keywords