DNA Methyltransferase 1 Targeting Using Guadecitabine Inhibits Prostate Cancer Growth by an Apoptosis-Independent Pathway
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DOI: 10.3390/cancers15102763
Abstract: Simple Summary We describe the unique role of guadecitabine (gDEC) activating lysine methyltransferases (KMTs) in association with prostate cancer inhibition. This study suggests that one consequence of DNMT1-targeting by gDEC is the upregulation of epigenetic… read more here.
Keywords: prostate cancer; apoptosis; gdec; guadecitabine ... See more keywords