Association of circulating soluble growth differentiation factor 15 with serum total testosterone in men with type 2 diabetes mellitus.
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes/metabolism research and reviews"
DOI: 10.1002/dmrr.3564
Abstract: AIMS Epidemiological studies consistently show that decreases in serum testosterone level are observed more frequently in men with type 2 diabetes mellitus (T2DM), while clinical investigations have demonstrated that an increased level of circulating growth… read more here.
Keywords: regression; diabetes mellitus; gdf; type diabetes ... See more keywords
Fragile X-Related Protein 1 (FXR1) Promotes Trophoblast Migration at Early Pregnancy via Downregulation of GDF-15 Expression
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive Sciences"
DOI: 10.1007/s43032-021-00693-1
Abstract: Fragile X-related protein 1 (FXR1) is an RNA-binding protein that can regulate specific mRNA decay in cells. Our previous study showed that FXR1 expression was significantly decreased in trophoblasts from patients with unexplained recurrent spontaneous… read more here.
Keywords: protein; fxr1; gdf; migration ... See more keywords
Urine Growth Differentiation Factor-15 is Not an Independent Biomarker of Cardio-Renal Interactions in Patients with Heart Failure
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cardiac Failure"
DOI: 10.1016/j.cardfail.2019.07.063
Abstract: Introduction Growth differentiation factor-15 (GDF-15) is a stress-responsive biomarker that is elevated in patients with heart failure (HF) and carries prognostic value. However, conditions other than HF can increase levels, making plasma concentration non-specific for… read more here.
Keywords: cardio renal; gdf; urinary gdf; patients heart ... See more keywords
Long-term prognostic value of growth differentiation factor-15 in acute coronary syndromes.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2019.07.014
Abstract: BACKGROUND Growth Differentiation Factor-15 (GDF-15) predicts death and cardiovascular events in acute coronary syndromes (ACS). We aimed to assess the long-term prognostic value of GDF-15 in ACS. METHODS We included 358 patients with ACS who… read more here.
Keywords: term; long term; prognostic value; gdf ... See more keywords
Potential biomarkers for early detection of diabetic kidney disease.
Sign Up to like & getrecommendations! Published in 2020 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2020.108082
Abstract: INTRODUCTION To assess the potential of galectin-3 and growth differentiation factor-15 (GDF-15) biomarkers for the early detection of diabetic kidney disease (DKD). METHODOLOGY This was a cross-sectional study conducted over a period of 1.2 years.… read more here.
Keywords: detection diabetic; biomarkers early; early detection; gdf ... See more keywords
Cadmium exposure and growth differentiation factor-15 (GDF-15) levels in non-smoking older adults.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental research"
DOI: 10.1016/j.envres.2021.112250
Abstract: BACKGROUND Cadmium (Cd) exposure is a risk factor for cardiovascular disease (CVD); however, understanding the effects of Cd at the cellular level remains incomplete. Since growth differentiation factor-15 (GDF-15) is a cytokine produced in many… read more here.
Keywords: non smoking; cadmium exposure; exposure; gdf ... See more keywords
Growth differentiation factor-15 and all-cause mortality in patients with suspected myocardial infarction.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2019.04.088
Abstract: BACKGROUND To assess the prognostic performance of Growth differentiation factor-15 (GDF-15) concentrations in unselected patients presenting with suspected acute myocardial infarction (AMI) and adjudication based on high-sensitivity cardiac troponin (hs-cTn). METHODS AND RESULTS In an… read more here.
Keywords: gdf; differentiation factor; year; ami ... See more keywords
The association between serum growth differentiation factor-15 and 3-month depression after acute ischemic stroke.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2019.09.037
Abstract: OBJECTIVE The aim of this study was to assess the association between serum growth differentiation factor-15(GDF-15) and 3-month depression after acute ischemic stroke. METHODS In this single-center prospective study, patients with first-ever acute ischemic stroke… read more here.
Keywords: depression; ischemic stroke; acute ischemic; gdf ... See more keywords
Targeting Unique Epitopes on Highly Similar Proteins GDF-11 and GDF-8 with Modified DNA Aptamers.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry"
DOI: 10.1021/acs.biochem.9b00760
Abstract: The mature forms of the TGF-β family members GDF-11 and GDF-8 are highly similar 25 kDa homodimers with 90% amino acid sequence identity and 99% similarity. Cross-reactivity of GDF-11 and GDF-8 binding reagents is common… read more here.
Keywords: affinity; selection; gdf; gdf gdf ... See more keywords
Elevated GDF-15 contributes to pulmonary inflammation upon cigarette smoke exposure
Sign Up to like & getrecommendations! Published in 2017 at "Mucosal Immunology"
DOI: 10.1038/mi.2017.3
Abstract: The molecular mechanisms underlying the pathogenesis of chronic obstructive pulmonary disease (COPD) are still unclear, however signaling pathways associated with lung development, such as the transforming growth factor (TGF)-β superfamily, could be implicated in COPD.… read more here.
Keywords: pulmonary inflammation; patients copd; cigarette smoke; inflammation ... See more keywords
Growth differentiating factor-15 and adiposity in young adults: The African-PREDICT study
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Obesity"
DOI: 10.1038/s41366-021-00803-8
Abstract: Circulating growth differentiation factor-15 (GDF-15) is a stress-responsive cytokine that increases in older individuals with established cardiovascular disease (CVD) and obesity. To address potential targets in primary prevention, we aimed to determine whether body weight,… read more here.
Keywords: waist; gdf; factor; growth ... See more keywords