Targeting Unique Epitopes on Highly Similar Proteins GDF-11 and GDF-8 with Modified DNA Aptamers.
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DOI: 10.1021/acs.biochem.9b00760
Abstract: The mature forms of the TGF-β family members GDF-11 and GDF-8 are highly similar 25 kDa homodimers with 90% amino acid sequence identity and 99% similarity. Cross-reactivity of GDF-11 and GDF-8 binding reagents is common… read more here.
Keywords: affinity; selection; gdf; gdf gdf ... See more keywords