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Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-98028-6
Abstract: Polycystic ovary syndrome (PCOS) is strongly associated with metabolic abnormalities, with 50–70% of patients exhibiting insulin resistance (IR), which significantly impacts the reproductive health of women in their reproductive years. Growth differentiation factor 15 (GDF15),…
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Keywords:
gdf15;
gdf15 levels;
insulin resistance;
pcos ... See more keywords
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Published in 2024 at "Experimental Physiology"
DOI: 10.1113/ep091815
Abstract: Glucagon‐like peptide‐1 receptor (GLP‐1R) agonists induce weight loss in patients with type 2 diabetes mellitus (T2DM), but the underlying mechanism is unclear. Recently, the mechanism by which metformin induces weight loss could be explained by…
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Keywords:
weight loss;
plasma gdf15;
gdf15 levels;
south asians ... See more keywords
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Published in 2021 at "Journal of Investigative Medicine"
DOI: 10.1136/jim-2021-001805
Abstract: Growth differentiation factor 15 (GDF15) is a stress-response cytokine which belongs to the transforming growth factor β superfamily. Although GDF15 was initially found to have a role in metabolic diseases, the association between GDF15 and…
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Keywords:
gdf15 levels;
gdf15;
obese subjects;
non obese ... See more keywords
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Published in 2022 at "Physiological Reports"
DOI: 10.14814/phy2.15293
Abstract: Plasma biomarkers that reflect energy balance disorders in people living with HIV (PLWH) remain limited. Growth differentiation factor 15 (GDF15) abundance in plasma of mice and humans induces negative energy balance but also becomes highly…
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Keywords:
plasma gdf15;
hiv;
gdf15;
levels plasma ... See more keywords
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Published in 2022 at "Endocrine Connections"
DOI: 10.1530/ec-22-0054
Abstract: Objective Growth differentiation factor-15 (GDF15), a key metabolic regulator, is associated with obesity and diabetes in which sex-specific differences have been reported. Thus, we assessed whether GDF15 could be dependent on sex in diabetes and/or…
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Keywords:
gdf15;
growth differentiation;
sex;
obesity ... See more keywords
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Published in 2019 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2018.00793
Abstract: Background: Recent studies have shown that growth differentiation factor 15 (GDF15), a member of the transforming growth factor-β (TGF-β)/bone morphogenetic protein (BMP) superfamily, plays an important role in appetite, type 2 diabetes, and cardiovascular diseases.…
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Keywords:
treatment;
gdf15 levels;
gdf15;
factor ... See more keywords
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Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.897097
Abstract: Purpose Sarcopenia is an important factor contributing to comorbidities in patients with chronic obstructive pulmonary disease (COPD) and is an independent risk factor for increased mortality. The diagnostic process for sarcopenia requires specific equipment and…
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Keywords:
patients copd;
sarcopenia patients;
factor;
sarcopenia ... See more keywords
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Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms262211073
Abstract: Growth differentiation factor 15 (GDF15) is a stress-response cytokine, which exerts different actions in physiological and pathological conditions. Thyroid disorders are common in the general population and their role on GDF15 levels has not been…
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Keywords:
thyroid function;
gdf15;
gdf15 levels;
effect thyroid ... See more keywords