Characterization of GDF2 Mutations and Levels of BMP9 and BMP10 in Pulmonary Arterial Hypertension.
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DOI: 10.1164/rccm.201906-1141oc
Abstract: OBJECTIVES Recently, rare heterozygous mutations in GDF2 were identified in patients with pulmonary arterial hypertension (PAH). GDF2 encodes the circulating bone morphogenetic protein, BMP9, which is a ligand for the BMP type 2 receptor (BMPR2).… read more here.
Keywords: gdf2 mutations; levels bmp9; bmp9 bmp10;