A targeted proteomic assay for the measurement of plasma proteoforms related to human aging phenotypes
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DOI: 10.1002/pmic.201600232
Abstract: Circulating polypeptides and proteins have been implicated in reversing or accelerating aging phenotypes, including growth/differentiation factor 8 (GDF8), GDF11, eotaxin, and oxytocin. These proteoforms, which are defined as the protein products arising from a single… read more here.
Keywords: proteomic assay; plasma; aging phenotypes; targeted proteomic ... See more keywords
Structural basis for potency differences between GDF8 and GDF11
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DOI: 10.1186/s12915-017-0350-1
Abstract: BackgroundGrowth/differentiation factor 8 (GDF8) and GDF11 are two highly similar members of the transforming growth factor β (TGFβ) family. While GDF8 has been recognized as a negative regulator of muscle growth and differentiation, there are… read more here.
Keywords: structural basis; gdf8 gdf11; basis potency; gdf11 ... See more keywords