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   Articles with "gdh" as a keyword



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Immunochromatographic test and ELISA for the detection of glutamate dehydrogenase (GDH) and A/B toxins as an alternative for the diagnosis of Clostridioides (Clostridium) difficile–associated diarrhea in foals and neonatal piglets

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recommendations! Published in 2020 at "Brazilian Journal of Microbiology"

DOI: 10.1007/s42770-020-00275-4

Abstract: Considering the lack of studies evaluating the performance of commercially available methods for diagnosis of Clostridioides ( Clostridium ) difficile infection (CDI) in animals, the present study aimed to assess an immunochromatographic test for detection… read more here.

Keywords: flow test; detection; gdh; test ... See more keywords
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Performance of laboratory tests for detection for Clostridioides difficile: A multicenter prospective study in Japan.

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recommendations! Published in 2019 at "Anaerobe"

DOI: 10.1016/j.anaerobe.2019.102107

Abstract: BACKGROUND The optimal and practical laboratory diagnostic approach for detection of Clostridioides difficile to aid in the diagnosis of C. difficile infection (CDI) is controversial. A two-step algorithm with initial detection of glutamate dehydrogenase (GDH)… read more here.

Keywords: detection; gdh; detection clostridioides; clostridioides difficile ... See more keywords
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GDH and toxin immunoassay for the diagnosis of Clostridioides (Clostridium) difficile infection is not a 'one size fit all' screening test.

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recommendations! Published in 2019 at "Diagnostic microbiology and infectious disease"

DOI: 10.1016/j.diagmicrobio.2018.12.010

Abstract: Diagnosing Clostridioides (Clostridium) difficile infection is challenged by lack of a clear gold standard. We sought to determine if the two-step algorithm (screening GDH and toxin lateral flow assay followed by tcdB PCR) would have… read more here.

Keywords: clostridium difficile; gdh; clostridioides clostridium; gdh toxin ... See more keywords
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Administration of chitosan-tripolyphosphate-DNA nanoparticles to knockdown glutamate dehydrogenase expression impairs transdeamination and gluconeogenesis in the liver.

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recommendations! Published in 2018 at "Journal of biotechnology"

DOI: 10.1016/j.jbiotec.2018.09.002

Abstract: Glutamate dehydrogenase (GDH) plays a major role in amino acid catabolism. To increase the current knowledge of GDH function, we analysed the effect of GDH silencing on liver intermediary metabolism from gilthead sea bream (Sparus… read more here.

Keywords: dehydrogenase; gdh; chitosan tripolyphosphate; administration chitosan ... See more keywords
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Stereoselective synthesis of a key chiral intermediate of (S)-Rivastigmine by AKR-GDH recombinant whole cells.

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recommendations! Published in 2019 at "Journal of biotechnology"

DOI: 10.1016/j.jbiotec.2018.11.016

Abstract: Herein, three aldo/ketoreductases (AKRs) were obtained and used to prepare N- ethyl-methyl-carbamic acid-3-[(1S)-hydroxy-ethyl]-phenyl ester ((S)-NEMCA-HEPE), which is a key intermediate of (S)-Rivastigmine. To avoid the usage of extra cofactors, the recombinant whole-cells containing AKRs and… read more here.

Keywords: gdh; reaction; recombinant whole; intermediate rivastigmine ... See more keywords
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Glutamate dehydrogenase is essential in the acclimation of Virgilia divaricata, a legume indigenous to the nutrient-poor Mediterranean-type ecosystems of the Cape Fynbos.

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recommendations! Published in 2019 at "Journal of plant physiology"

DOI: 10.1016/j.jplph.2019.153053

Abstract: Glutamate dehydrogenase (NAD(H)- GDH, EC 1.4.1.2) is an important enzyme in nitrogen (N) metabolism. It serves as a link between C and N metabolism, in its role of assimilating ammonia into glutamine or deaminating glutamate… read more here.

Keywords: gdh; divaricata legume; virgilia divaricata; mediterranean type ... See more keywords

Ammonium removal by erythrocyte-bioreactors based on glutamate dehydrogenase from Proteus sp. jointly with porcine heart alanine aminotransferase

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recommendations! Published in 2022 at "Scientific Reports"

DOI: 10.1038/s41598-022-09435-y

Abstract: Excessive ammonium blood concentration causes many serious neurological complications. The medications currently used are not very effective. To remove ammonium from the blood, erythrocyte-bioreactors containing enzymes that processing ammonium have been proposed. The most promising… read more here.

Keywords: proteus; ammonium removal; gdh; erythrocyte bioreactors ... See more keywords
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The effects of fullerene on photosynthetic apparatus, chloroplast-encoded gene expression and nitrogen assimilation in Zea mays under cobalt stress.

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recommendations! Published in 2022 at "Physiologia plantarum"

DOI: 10.1111/ppl.13720

Abstract: Carbon nanostructures, such as the water-soluble fullerene (FLN) derivatives, are considered perspective agents for agriculture. FLN can be a novel nano-agent modulating plant response against stress conditions. However, the mechanism underlying the impacts of FLN… read more here.

Keywords: gdh; stress; cobalt stress; assimilation ... See more keywords
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Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia

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recommendations! Published in 2021 at "Frontiers in Neuroscience"

DOI: 10.3389/fnins.2021.646291

Abstract: Impaired liver function may lead to hyperammonemia and risk for hepatic encephalopathy. In brain, detoxification of ammonia is mediated mainly by glutamine synthetase (GS) in astrocytes. This requires a continuous de novo synthesis of glutamate,… read more here.

Keywords: gdh; hyperammonemia; glutamate; ammonia ... See more keywords
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Construction of Bi-Enzyme Self-Assembly Clusters Based on SpyCatcher/SpyTag for the Efficient Biosynthesis of (R)-Ethyl 2-hydroxy-4-phenylbutyrate

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recommendations! Published in 2023 at "Biomolecules"

DOI: 10.3390/biom13010091

Abstract: Cascade reactions catalyzed by multi-enzyme systems are important in science and industry and can be used to synthesize drugs and nutrients. In this study, two types of macromolecules of bi-enzyme self-assembly clusters (BESCs) consisting of… read more here.

Keywords: gdh; spycatcher spytag; cpcr; ethyl ... See more keywords
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Structural Basis for the Binding of Allosteric Activators Leucine and ADP to Mammalian Glutamate Dehydrogenase

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recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms231911306

Abstract: Glutamate dehydrogenase (GDH) plays a key role in the metabolism of glutamate, an important compound at a cross-road of carbon and nitrogen metabolism and a relevant neurotransmitter. Despite being one of the first discovered allosteric… read more here.

Keywords: gdh; allosteric activators; structural basis; leucine adp ... See more keywords