Oestrogen receptor α in T cells controls the T cell immune profile and glucose metabolism in mouse models of gestational diabetes mellitus
Sign Up to like & getrecommendations! Published in 2021 at "Diabetologia"
DOI: 10.1007/s00125-021-05447-x
Abstract: The imbalance between maternal insulin resistance and a relative lack of insulin secretion underlies the pathogenesis of gestational diabetes mellitus (GDM). Alterations in T cell subtypes and increased levels of circulating proinflammatory cytokines have been… read more here.
Keywords: insulin; oestrogen; gdm; gdm mice ... See more keywords
Long-noncoding RNA HOXA transcript at the distal tip ameliorates the insulin resistance and hepatic gluconeogenesis in mice with gestational diabetes mellitus via the microRNA-423-5p/wingless-type MMTV integration site family member 7A axis
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2076982
Abstract: ABSTRACT Long-noncoding RNA HOXA transcript at the distal tip (HOTTIP) has been probed to exert essential effects on diabetes progression, while its function in gestational diabetes mellitus (GDM) remains unclear. This study was committed to… read more here.
Keywords: mir 423; gdm mice; wnt7a; hottip ... See more keywords
Barbaloin Treatment Contributes to the Rebalance of Glucose and Lipid Homeostasis of Gestational Diabetes Mellitus Mice
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DOI: 10.1177/1559325820984910
Abstract: Aloe vera L has been shown to possess hypoglycemic and hypolipidemic effects on type 2 diabetic patients, and its major benefits may be linked to barbaloin, which is a major component of Aloe vera L.… read more here.
Keywords: gestational diabetes; barbaloin treatment; gdm mice; diabetes mellitus ... See more keywords
Downregulation of microRNA-342-3p Eases Insulin Resistance and Liver Gluconeogenesis via Regulating Rfx3 in Gestational Diabetes Mellitus.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in eukaryotic gene expression"
DOI: 10.1615/critreveukaryotgeneexpr.2022043275
Abstract: Gestational diabetes mellitus (GDM) is a worldwide public health problem. MicroRNAs (miRNAs) have been reported to be associated with GDM progression. We intended to figure out the function of miR-342-3p in the insulin resistance (IR)… read more here.
Keywords: gdm mice; downregulation; liver gluconeogenesis; mir 342 ... See more keywords
FGF4, A New Potential Regulator in Gestational Diabetes Mellitus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.827617
Abstract: Background: Gestational diabetes mellitus (GDM) is associated with adverse maternal and neonatal outcomes, however the underlying mechanisms remain elusive. The aim of this study was to find efficient regulator of FGFs in response to the… read more here.
Keywords: gdm; gdm mice; fgf4 new; gestational diabetes ... See more keywords
Polyphyllin I alleviates inflammatory injury in mice with gestational diabetes through AMPK pathway.
Sign Up to like & getrecommendations! Published in 2022 at "General physiology and biophysics"
DOI: 10.4149/gpb_2022006
Abstract: Our study aimed to detect the effects of polyphyllin I (PPI) on relieving gestational diabetes mellitus (GDM), and the possible mechanism. A mouse model of GDM was constructed. The effects of PPI on GDM mice… read more here.
Keywords: gdm; inflammatory injury; gdm mice; ampk pathway ... See more keywords