High-Throughput Assay for RhoGEFs Based on the Transcreener® GDP Assay.
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DOI: 10.1007/978-1-4939-8612-5_12
Abstract: We describe a high-throughput screening (HTS)-compatible method for detecting GTPase exchange factor (GEF) activity based on stimulation of GDP formation by Rho GTPases. The method is based on the fact that GDP dissociation is the… read more here.
Keywords: throughput assay; transcreener gdp; gdp formation; high throughput ... See more keywords