Northern European Salmo trutta (L.) populations are genetically divergent across geographical regions and environmental gradients
Sign Up to like & getrecommendations! Published in 2020 at "Evolutionary Applications"
DOI: 10.1111/eva.12877
Abstract: The salmonid fish Brown trout is iconic as a model for the application of conservation genetics to understand and manage local interspecific variation. However, there is still scant information about relationships between local and large‐scale… read more here.
Keywords: gea; population structure; geographical regions; across geographical ... See more keywords
Abstract CT156: MCLA-158 (petosemtamab), an IgG1 bispecific antibody targeting EGFR and LGR5, in advanced gastric/esophageal adenocarcinoma (GEA)
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-ct156
Abstract: The epidermal growth factor receptor (EGFR) is a known driver of cancer growth and the leucine-rich, repeat-containing, G-protein coupled receptor 5 (LGR5) is a transmembrane receptor expressed on cancer stem cells. Petosemtamab is a human,… read more here.
Keywords: lgr5; igg1 bispecific; petosemtamab; bispecific antibody ... See more keywords
Molecular biomarkers in gastro-esophageal cancer: recent developments, current trends and future directions
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Cell International"
DOI: 10.1186/s12935-018-0594-z
Abstract: Gastro-esophageal adenocarcinomas (GEA) represent a severe global health burden and despite improvements in the multimodality treatment of these malignancies the prognosis of patients remains poor. HER2 overexpression/amplification has been the first predictive biomarker approved in… read more here.
Keywords: gea; biomarker; treatment; gastro esophageal ... See more keywords
Molecular profiling of a gastroesophageal adenocarcinoma (GEA) multicohort using next-generation sequencing (NGS).
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.4_suppl.494
Abstract: 494 Background: The mutational landscape of GEA is rapidly evolving with the identification of promising molecular targets. However, histological subtypes are insufficient to capture the molecular heterogeneity in these patients (pts). We aim to assess… read more here.
Keywords: molecular profiling; profiling gastroesophageal; gastroesophageal adenocarcinoma; gea ... See more keywords
Commentary: Evaluation of Phase-Amplitude Coupling in Resting State Magnetoencephalographic Signals: Effect of Surrogates and Evaluation Approach
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Computational Neuroscience"
DOI: 10.3389/fncom.2018.00026
Abstract: Using Human Connectome Project (HCP) data, Gohel et al. (2016) (GEA) recently reported that “resting-state MEG signals failed to exhibit ubiquitous phase-amplitude coupling (PAC) phenomenon, contrary to what has been suggested” by Florin and Baillet… read more here.
Keywords: phase amplitude; gea; evaluation; resting state ... See more keywords
Cytopathologic features of human papillomavirus–independent, gastric-type endocervical adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pathology and Translational Medicine"
DOI: 10.4132/jptm.2022.07.05
Abstract: Background Gastric-type endocervical adenocarcinoma (GEA) is unrelated to human papillomavirus (HPV) infection and is clinically aggressive compared with HPV-associated usual-type endocervical adenocarcinoma (UEA). The cytological diagnosis falls short of a definitive diagnosis of GEA and… read more here.
Keywords: endocervical adenocarcinoma; gea; gastric type; type endocervical ... See more keywords