Articles with "gelma" as a keyword



GelMA and Biomimetic Culture Allow the Engineering of Mineralized, Adipose, and Tumor Tissue Human Microenvironments for the Study of Advanced Prostate Cancer In Vitro and In Vivo

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Published in 2023 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202201701

Abstract: Increasing evidence shows bone marrow (BM)‐adipocytes as a potentially important contributor in prostate cancer (PCa) bone metastases. However, a lack of relevant models has prevented the full understanding of the effects of human BM‐adipocytes in… read more here.

Keywords: gelma; prostate cancer; mineralized adipose; tumor ... See more keywords

Gelatin Methacryloyl Hydrogel, from Standardization, Performance, to Biomedical Application.

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Published in 2023 at "Advanced healthcare materials"

DOI: 10.1002/adhm.202300395

Abstract: Gelatin methacryloyl (GelMA), a photocurable hydrogel, is widely used in 3D culture, particularly in 3D bioprinting, due to its high biocompatibility, tunable physicochemical properties, and excellent formability. However, as the properties and performances of GelMA… read more here.

Keywords: gelma; methacryloyl hydrogel; gelatin methacryloyl; hydrogel standardization ... See more keywords

Neutrophil Granulopoiesis Optimized Through Ex Vivo Expansion of Hematopoietic Progenitors in Engineered 3D Gelatin Methacrylate Hydrogels

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Published in 2024 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202301966

Abstract: Neutrophils are the first line of defense of the innate immune system. In response to methicillin‐resistant Staphylococcus aureus infection in the skin, hematopoietic stem, and progenitor cells (HSPCs) traffic to wounds and undergo extramedullary granulopoiesis,… read more here.

Keywords: granulopoiesis; gelatin methacrylate; gelma; expansion ... See more keywords

Highly Stretchable, Self‐Healable, and Conductive Gelatin Methacryloyl Hydrogel for Long‐Lasting Wearable Tactile Sensors

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Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202502678

Abstract: Constructing hydrogels with both remarkable mechanical and self‐healing properties is highly desirable for soft electronics, yet remains challenging due to conflicting demands on chemical bonds and polymer chain mobility. Herein, a highly stretchable, self‐healing, and… read more here.

Keywords: hydrogel; stretchable self; self healing; gelma ... See more keywords

Microfluidic Production of Zwitterion Coating Microcapsules with Low Foreign Body Reactions for Improved Islet Transplantation.

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Published in 2022 at "Small"

DOI: 10.1002/smll.202202596

Abstract: Islet transplantation is a promising strategy for type 1 diabetes mellitus (T1DM) treatment, whereas implanted-associated foreign body reaction (FBR) usually induces the necrosis of transplanted islets and leads to the failure of glycemic control. Benefiting… read more here.

Keywords: zwitterion; gelma; foreign body; islet transplantation ... See more keywords

Gastric Cancer Models Developed via GelMA 3D Bioprinting Accurately Mimic Cancer Hallmarks, Tumor Microenvironment Features, and Drug Responses.

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Published in 2025 at "Small"

DOI: 10.1002/smll.202409321

Abstract: Current in vitro models for gastric cancer research, such as 2D cell cultures and organoid systems, often fail to replicate the complex extracellular matrix (ECM) found in vivo. For the first time, this study utilizes… read more here.

Keywords: cancer; cancer hallmarks; gastric cancer; drug ... See more keywords

Gelatin methacryloyl as environment for chondrocytes and cell delivery to superficial cartilage defects

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Published in 2021 at "Journal of Tissue Engineering and Regenerative Medicine"

DOI: 10.1002/term.3273

Abstract: Cartilage damage typically starts at its surface, either due to wear or trauma. Treatment of these superficial defects is important in preventing degradation and osteoarthritis. Biomaterials currently used for deep cartilage defects lack appropriate properties… read more here.

Keywords: superficial cartilage; surface; gelatin methacryloyl; gelma ... See more keywords

Platelet lysate functionalized GelMA microspheres for improving angiogenesis in endodontic regeneration.

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Published in 2021 at "Acta biomaterialia"

DOI: 10.1016/j.actbio.2021.09.024

Abstract: Rapid angiogenesis is one of the challenges in endodontic regeneration. Recently, tailored polymeric microsphere system that loaded pro-angiogenic growth factors (GFs) is promising in facilitating vascularization in dental pulp regeneration. In addition, the synergistic effect… read more here.

Keywords: gelma; regeneration; microsphere system; endodontic regeneration ... See more keywords

Submerged and non-submerged 3D bioprinting approaches for the fabrication of complex structures with the hydrogel pair GelMA and alginate/methylcellulose

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Published in 2021 at "Additive Manufacturing"

DOI: 10.1016/j.addma.2020.101640

Abstract: Abstract The extrusion-based bioprinting of hydrogels such as gelatin methacrylate (GelMA) into structures with complex shape suffers from poor printability due to their low viscosity. The present study deals with hydrogel materials by using the… read more here.

Keywords: non submerged; gelma; bioprinting; cell ... See more keywords

Seamless and early gap healing of osteochondral defects by autologous mosaicplasty combined with bioactive supramolecular nanofiber-enabled gelatin methacryloyl (BSN-GelMA) hydrogel

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Published in 2022 at "Bioactive Materials"

DOI: 10.1016/j.bioactmat.2022.03.038

Abstract: Autologous mosaicplasty is a common approach used to treat osteochondral defects in clinical practice. Gap integration between host and transplanted plugs requires bone tissue reservation and hyaline cartilage regeneration without uneven surface, graft necrosis and… read more here.

Keywords: gap; bsn gelma; gelma; osteochondral defects ... See more keywords

Acoustic transmitted electrospun fibrous membranes for tympanic membrane regeneration

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Published in 2021 at "Chemical Engineering Journal"

DOI: 10.1016/j.cej.2021.129536

Abstract: Abstract Scaffold with good acoustic transmission effect, high mechanical strength and good biocompatibility is a challenge for tympanic membrane (TM) regeneration. A new strategy using Tannic acid (TA) as the structural matrix crosslinked with Gelatin… read more here.

Keywords: acoustic transmitted; transmitted electrospun; membrane; electrospun fibrous ... See more keywords