A one-step synthesis of gem-difluoroolefins from alcohols
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2020.109649
Abstract: Abstract The development of efficient protocols for the synthesis of gem-difluoroolefins has received increasing attention. Given the ubiquity of hydroxyl group in biologically active molecules and synthetic intermediates, we developed a one-step protocol for the… read more here.
Keywords: step synthesis; gem difluoroolefins; gem; synthesis gem ... See more keywords
An efficient method for the synthesis of gem-difluoroolefins
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2016.12.070
Abstract: A series of gem-difluoroolefin derivatives were synthesized in moderate to good yields by the reaction of α,α-difluoro-β-carbonyl benzothiazol-2-yl sulfones (DFBTs) with various carbon nucleophiles. Using dl-proline as organocatalyst, the reaction of DFBT with acetone gave… read more here.
Keywords: efficient method; gem; gem difluoroolefins; synthesis gem ... See more keywords