Gemcitabine and cisplatin regimen facilitates prognosis of advanced nasopharyngeal carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1575
Abstract: This study was conducted to assess the efficacy and adverse effects of GP (gemcitabine + cisplatin) regimen and FP (fluouracil + cisplatin) regimen in treatment of advanced nasopharyngeal carcinoma. Systematic online searches were performed in… read more here.
Keywords: regimen facilitates; gemcitabine cisplatin; cisplatin regimen; advanced nasopharyngeal ... See more keywords
Radiotherapy vs sequential pegaspargase, gemcitabine, cisplatin and dexamethasone and radiotherapy in newly diagnosed early natural killer/T‐cell lymphoma: A randomized, controlled, open‐label, multicenter study
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Cancer"
DOI: 10.1002/ijc.33329
Abstract: To compare the efficacy and safety of radiotherapy (RT) and chemotherapy of pegaspargase, gemcitabine, cisplatin and dexamethasone (DDGP) combined with RT in newly diagnosed stage I‐II natural killer/T‐cell lymphoma (NKTL), we designed a randomized, controlled,… read more here.
Keywords: radiotherapy; group; ddgp combined; gemcitabine cisplatin ... See more keywords
Co-delivery of gemcitabine and cisplatin via Poly (L-glutamic acid)-g-methoxy poly (ethylene glycol) micelle to improve the in vivo stability and antitumor effect.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutical research"
DOI: 10.1007/s11095-021-03139-0
Abstract: PURPOSE The intention of the study was to co-delivery gemcitabine and cisplatin with totally different nature by prodrug and micelle strategy to improve its in vivo stability and antitumor effect. METHODS A prodrug of gemcitabine… read more here.
Keywords: gem; gemcitabine cisplatin; mpeg plg;
GDC-0980 (apitolisib) treatment with gemcitabine and/or cisplatin synergistically reduces cholangiocarcinoma cell growth by suppressing the PI3K/Akt/mTOR pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.06.011
Abstract: Since conventional chemotherapy (gemcitabine and cisplatin) has marginal survival benefit in patients with advanced cholangiocarcinoma (CCA), an effective targeted therapeutic agent is urgently required. Activation of the PI3K/Akt/mTOR signaling pathway is frequently observed in CCA,… read more here.
Keywords: pi3k akt; cell growth; gemcitabine cisplatin; mtor ... See more keywords
Endostar Combined with Gemcitabine and Cisplatin Chemotherapy for Patients with Metastatic Nasopharyngeal Carcinoma: an Update
Sign Up to like & getrecommendations! Published in 2018 at "Translational Oncology"
DOI: 10.1016/j.tranon.2018.01.002
Abstract: OBJECTIVE: A previous phase-2 trial to assess the addition of Endostar to gemcitabine and cisplatin (GC) chemotherapy showed that it improves prognosis in metastatic nasopharyngeal carcinoma (M-NPC) but the study cohort was small. We wished… read more here.
Keywords: chemotherapy; cisplatin chemotherapy; gemcitabine cisplatin; day ... See more keywords
Translating the ABC-02 trial into daily practice: outcome of palliative treatment in patients with unresectable biliary tract cancer treated with gemcitabine and cisplatin
Sign Up to like & getrecommendations! Published in 2018 at "Acta Oncologica"
DOI: 10.1080/0284186x.2017.1418532
Abstract: Abstract Background: Biliary tract cancer (BTC) is an uncommon cancer with an unfavorable prognosis. Since 2010, the standard of care for patients with unresectable BTC is palliative treatment with gemcitabine plus cisplatin, based on the… read more here.
Keywords: cisplatin; group; abc trial; patients unresectable ... See more keywords
Pemetrexed/cisplatin versus gemcitabine/cisplatin as first-line treatment for Egyptian patients with malignant pleural mesothelioma
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz266.013
Abstract: Abstract Background The combination of cisplatin and pemetrexed is considered the standard of care front line regimen for malignant pleural mesothelioma (MPM). Several phase II trials demonstrated comparable response and survival rates with the use… read more here.
Keywords: line; treatment; cisplatin; pleural mesothelioma ... See more keywords
Clinical outcomes of gemcitabine, cisplatin plus S-1 in patients with advanced biliary tract cancer
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DOI: 10.1093/annonc/mdz338.010
Abstract: Abstract Background Gemcitabine plus cisplatin has been the standard palliative chemotherapy for patients with advanced biliary tract cancer (aBTC). Recently, the survival benefit of combination chemotherapy with gemcitabine, cisplatin, and S-1 (GCS) was reported, and… read more here.
Keywords: biliary tract; tract cancer; gemcitabine cisplatin; advanced biliary ... See more keywords
Gemcitabine/Cisplatin therapy for an urothelial carcinoma patient undergoing hemodialysis: a case report
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DOI: 10.1093/annonc/mdz343.025
Abstract: Abstract Background Gemcitabine/Cisplatin (GC) therapy is first-line chemotherapy for advanced urothelial carcinoma (UC). The Renal Impairment Clinical Practice Guidelines 2016 suggest that, Cisplatin (CDDP) may be administered by up to 50% of standard dose for… read more here.
Keywords: therapy; gemcitabine cisplatin; cisplatin therapy; patient ... See more keywords
Induction gemcitabine and cisplatin in locoregionally advanced nasopharyngeal carcinoma
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DOI: 10.1186/s40880-019-0385-5
Abstract: The standard of care for patients with locoregionally advanced nasopharyngeal carcinoma is concurrent platinum-based chemoradiotherapy. Existing literature have demonstrated that the addition of gemcitabine and cisplatin as induction chemotherapy in locoregionally advanced nasopharyngeal carcinoma may… read more here.
Keywords: carcinoma; locoregionally advanced; gemcitabine cisplatin; advanced nasopharyngeal ... See more keywords
Gemcitabine and cisplatin plus ramucirumab or merestinib or placebo in first-line treatment for advanced or metastatic biliary tract cancer: A double-blind, randomized phase II trial.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.4_suppl.tps509
Abstract: TPS509Background: Angiogenesis and aberrant MET signaling are implicated in the pathogenesis and progression of invasive biliary tract cancers (BTC), including adenocarcinomas of the gallbladder, intra- and extra-hepatic bile ducts, and ampulla of Vater. JSBF (NCT02711553)… read more here.
Keywords: biliary tract; advanced metastatic; placebo first; treatment ... See more keywords