Combinatorial Efficacy and Toxicity of an Engineered Toxin Body MT-3724 with Gemcitabine and Oxaliplatin in Relapsed or Refractory Diffuse Large B Cell Lymphoma
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DOI: 10.1080/07357907.2022.2162073
Abstract: Abstract MT-3724 is an engineered direct-kill immunotoxin comprised of a CD20-specific scFv fused to a Shiga-like toxin subunit. In this phase IIa study, eight patients with relapsed diffuse large B-cell lymphoma were treated with MT-3724… read more here.
Keywords: cell lymphoma; gemcitabine oxaliplatin; toxin; large cell ... See more keywords
Effects of Gemcitabine and Oxaliplatin Combined with Apatinib on Immune Function and Levels of SIL-2R and sicAM-1 in Patients with Gallbladder Cancer
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DOI: 10.1155/2022/4959840
Abstract: Objective The aim of this study was to determine how gemcitabine, oxaliplatin combination, and apatinib affect immune function and SIL-2R and sicAM-1 levels in patients with gallbladder cancer. Methods Retrospective analysis of 116 patients with… read more here.
Keywords: gemcitabine oxaliplatin; patients gallbladder; group; immune function ... See more keywords
Synergistic Antitumor Effect and Mechanism of Chidamide Combined with Gemcitabine, Oxaliplatin or Zanubrutinib in Diffuse Large B-Cell Lymphoma
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DOI: 10.1182/blood-2020-133487
Abstract: Aims: To observe the synergistic antitumor effect of chidamide (a novel orally benzamide class of histone deacetylase inhibitors, HDACi) combined with gemcitabine, oxaliplatin or zanubrutinib (a second generation Bruton's tyrosine kinase (BTK) inhibitor) in diffuse… read more here.
Keywords: chidamide; cell lines; gemcitabine oxaliplatin; dlbcl cell ... See more keywords
Real-World Evidence on Palliative Gemcitabine and Oxaliplatin (GemOx) Combination Chemotherapy in Advanced Biliary Tract Cancer
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DOI: 10.3390/cancers13143507
Abstract: Simple Summary Cancers of the biliary tract are rare but severe with high mortality rates. Randomised controlled trials suggest that chemotherapies such as gemcitabine and oxaliplatin (GemOx) may relieve symptoms and prolong life, but less… read more here.
Keywords: biliary tract; real world; tract; oxaliplatin gemox ... See more keywords