Blockade of endothelin receptor A enhances the therapeutic efficacy of gemcitabine in pancreatic cancer cells.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.04.118
Abstract: Pancreatic adenocarcinoma is currently one of the leading causes of cancer-related death worldwide. The high rate of mortality in pancreatic cancer patients is due to the inability to detect early-stage disease and the disease being… read more here.
Keywords: pancreatic cancer; gemcitabine pancreatic; cancer cells; cancer ... See more keywords
Barriers and opportunities for gemcitabine in pancreatic cancer therapy
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Physiology - Cell Physiology"
DOI: 10.1152/ajpcell.00331.2022
Abstract: Pancreatic ductal adenocarcinoma (PDA) has become one of the leading causes of cancer-related deaths across the world. A lack of durable responses to standard-of-care chemotherapies renders its treatment particularly challenging and largely contributes to the… read more here.
Keywords: barriers opportunities; therapy; opportunities gemcitabine; physiology ... See more keywords