Comparison of FOLFIRINOX vs Gemcitabine Plus Nab-Paclitaxel as First-Line Chemotherapy for Metastatic Pancreatic Ductal Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.16199
Abstract: Key Points Question Is there a difference in survival or toxic effects between the main first-line therapies used for metastatic pancreatic cancer? Findings In this comparative effectiveness study that included 1102 patients, FOLFIRINOX (combined leucovorin… read more here.
Keywords: gemcitabine plus; metastatic pancreatic; plus nab; first line ... See more keywords
The renal safety and efficacy of combined gemcitabine plus cisplatin and gemcitabine plus carboplatin chemotherapy in Chinese patients with a solitary kidney after nephroureterectomy
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DOI: 10.1007/s00280-017-3316-7
Abstract: PurposeThe renal safety of cisplatin-based chemotherapy has not been investigated in patients with urothelial carcinoma of the upper urinary tract (UUT-UC) who retain a solitary kidney after nephroureterectomy. This study aimed to assess and compare… read more here.
Keywords: chemotherapy; renal safety; gemcitabine plus; solitary kidney ... See more keywords
Efficacy and Safety of Gemcitabine Plus Either Taxane or Carboplatin in the First‐Line Setting of Metastatic Urothelial Carcinoma: A Systematic Review and Meta‐Analysis
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Genitourinary Cancer"
DOI: 10.1016/j.clgc.2016.05.003
Abstract: &NA; Although gemcitabine plus carboplatin (GCa) is the conventional first‐line chemotherapy for cisplatin‐ineligible metastatic urothelial carcinoma, its results are suboptimal. A meta‐analysis evaluated the results of gemcitabine with either carboplatin or a taxane (GT). Literature… read more here.
Keywords: first line; analysis; gca; gemcitabine plus ... See more keywords
Gemcitabine plus nab-paclitaxel in older patients with metastatic pancreatic cancer: A post-hoc analysis of the real-world data of a multicenter study (the NAPOLEON study).
Sign Up to like & getrecommendations! Published in 2021 at "Journal of geriatric oncology"
DOI: 10.1016/j.jgo.2021.06.011
Abstract: OBJECTIVES This study aimed to examine the efficacy and safety of gemcitabine plus nab-paclitaxel (GnP) in older patients with metastatic pancreatic cancer (MPC), especially those ≥75 years old. MATERIALS AND METHODS This study retrospectively enrolled… read more here.
Keywords: nab paclitaxel; group; study; plus nab ... See more keywords
Gemcitabine plus S-1 for metastatic pancreatic cancer
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DOI: 10.1097/md.0000000000012836
Abstract: Abstract To investigate the treatment effects of gemcitabine plus S-1 (GS) for metastatic pancreatic cancer in our institution. Data from 41 patients with metastatic pancreatic cancer treated with GS regimen in West China Hospital, Sichuan… read more here.
Keywords: plus metastatic; metastatic pancreatic; gemcitabine plus; pancreatic cancer ... See more keywords
Predictors of Poor Pathological Response to Neoadjuvant Gemcitabine Plus S-1 Chemotherapy in Patients With Pancreatic Ductal Adenocarcinoma
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DOI: 10.1097/mpa.0000000000001826
Abstract: Objectives Although neoadjuvant chemotherapy (NAC)–gemcitabine plus S-1 (GS) has been reported to have a survival benefit in patients with resectable pancreatic ductal adenocarcinoma (PDAC), optimal candidates for NAC-GS have not been clearly identified. Methods A… read more here.
Keywords: chemotherapy; gemcitabine plus; pancreatic ductal; ductal adenocarcinoma ... See more keywords
Sarcopenia: Prognostic Value for Unresectable Pancreatic Ductal Adenocarcinoma Patients Treated With Gemcitabine Plus Nab-Paclitaxel.
Sign Up to like & getrecommendations! Published in 2022 at "Pancreas"
DOI: 10.1097/mpa.0000000000001985
Abstract: OBJECTIVE The aim of the study was to clarify the association of skeletal muscle mass and the prognosis of unresectable pancreatic ductal adenocarcinoma (PDAC) treated with gemcitabine plus nab-paclitaxel (GnP). METHODS We included 124 unresectable… read more here.
Keywords: sarcopenia; unresectable pancreatic; gemcitabine plus; treated gemcitabine ... See more keywords
Abstract OT2-05-01: A phase II randomized trial of gemcitabine plus cisplatin(GP) vs. gemcitabine plus carboplatin (GC) as the first-line treatment for patients with metastatic triple negative breast cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs17-ot2-05-01
Abstract: Background: Triple-negative breast cancer (TNBC) is an aggressive disease with limited treatment options and poor prognosis . Gemcitabine plus carboplatin (GC) is one of the preferred chemotherapeutic regimens for patients with metastatic triple-negative breast cancer(mTNBC),… read more here.
Keywords: gemcitabine; first line; breast cancer; cancer ... See more keywords
Clinical outcomes of chemotherapy in patients with undifferentiated carcinoma of the pancreas: a retrospective multicenter cohort study
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DOI: 10.1186/s12885-020-07462-4
Abstract: Background Undifferentiated carcinoma (UC) of the pancreas is a rare subtype of pancreatic cancer. Although UC has been considered a highly aggressive malignancy, no clinical studies have addressed the efficacy of chemotherapy for unresectable UC.… read more here.
Keywords: nab paclitaxel; gemcitabine; study; plus nab ... See more keywords
Complete regression of pulmonary squamous carcinoma in IPF following gemcitabine plus cisplatin: a case report and literature review
Sign Up to like & getrecommendations! Published in 2020 at "BMC Pulmonary Medicine"
DOI: 10.1186/s12890-020-1094-1
Abstract: Background Lung cancer is one of the most common co-morbid conditions in patients with idiopathic pulmonary fibrosis (IPF) and negatively affects the prognosis of IPF; Current guidelines for the management of IPF do not give… read more here.
Keywords: squamous carcinoma; gemcitabine plus; case; following gemcitabine ... See more keywords
A phase Ib/II pilot trial with nab-paclitaxel plus gemcitabine plus cisplatin in patients (pts) with stage IV pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.4_suppl.341
Abstract: 341Background: Genomes of metastatic pancreatic cancers frequently contain intrachromosomal aberrations indicating DNA repair abnormalities associated with sensitivity to DNA damaging agents such as the platinums. Cisplatin was added to a nab-paclitaxel + gemcitabine regimen, which… read more here.
Keywords: nab paclitaxel; cisplatin patients; stage pancreatic; plus cisplatin ... See more keywords