Pharmacokinetic Interactions Between Gemigliptin and Metformin, and Potential Differences in the Pharmacokinetic Profile of Gemigliptin Between the Mexican and Korean Populations: A Randomized, Open-label Study in Healthy Mexican Volunteers.
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DOI: 10.1016/j.clinthera.2018.08.015
Abstract: PURPOSE The aim of this study was to assess the pharmacokinetic interactions between a newly developed dipeptidyl peptidase (DPP)-4 inhibitor, gemigliptin, and metformin in healthy Mexican male volunteers, and the differences in the pharmacokinetic profile… read more here.
Keywords: gemigliptin metformin; pharmacokinetic profile; gemigliptin; profile gemigliptin ... See more keywords
Pharmacokinetic and pharmacodynamic interaction of DWP16001, a sodium–glucose cotransporter 2 inhibitor, with gemigliptin and metformin in healthy adults
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DOI: 10.1111/bcp.15632
Abstract: DWP16001, a novel sodium–glucose cotransporter 2 inhibitor, is under clinical development for the treatment of type 2 diabetes mellitus. This study aimed to explore the pharmacokinetics (PK) and pharmacodynamics interaction of DWP16001 with gemigliptin and… read more here.
Keywords: cotransporter inhibitor; glucose cotransporter; gemigliptin metformin; dwp16001 ... See more keywords
Pharmacokinetic Equivalence of the High Dose Strength Fixed-Dose Combination Tablet of Gemigliptin/Metformin Sustained Release (SR) and Individual Component Gemigliptin and Metformin XR Tablets in Healthy Subjects
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DOI: 10.3346/jkms.2018.33.e258
Abstract: Background In type 2 diabetes mellitus therapy, fixed-dose combination (FDC) can offer not only benefits in glucose control via the combined use of agents, but also increase patient compliance. The aim of this study was… read more here.
Keywords: gemigliptin metformin; gemigliptin; tablet gemigliptin; pharmacokinetic equivalence ... See more keywords