SNP discovery of PRKAB1 gene and their associations with growth traits in goats.
Sign Up to like & getrecommendations! Published in 2021 at "Animal biotechnology"
DOI: 10.1080/10495398.2021.1920426
Abstract: AMPK plays an important role in regulating the metabolism of carbohydrate, lipid and protein in an organism, and is considered to be a key regulator of cellular energy homeostasis. In recent years, attention has been… read more here.
Keywords: prkab1; growth traits; gene associations; prkab1 gene ... See more keywords
eDGAR: a database of Disease-Gene Associations with annotated Relationships among genes
Sign Up to like & getrecommendations! Published in 2017 at "BMC Genomics"
DOI: 10.1186/s12864-017-3911-3
Abstract: BackgroundGenetic investigations, boosted by modern sequencing techniques, allow dissecting the genetic component of different phenotypic traits. These efforts result in the compilation of lists of genes related to diseases and show that an increasing number… read more here.
Keywords: disease gene; disease; among genes; gene associations ... See more keywords
Systematic identification of latent disease-gene associations from PubMed articles
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0191568
Abstract: Recent scientific advances have accumulated a tremendous amount of biomedical knowledge providing novel insights into the relationship between molecular and cellular processes and diseases. Literature mining is one of the commonly used methods to retrieve… read more here.
Keywords: disease gene; gene associations; latent disease; disease ... See more keywords
Economic Value of Pharmacogenetic Testing for Cancer Drugs with Clinically Relevant Drug-Gene Associations: A Systematic Literature Review.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of managed care & specialty pharmacy"
DOI: 10.18553/jmcp.2019.25.2.260
Abstract: BACKGROUND Pharmacogenetic testing can provide predictive insights about the efficacy and safety of drugs used in cancer treatment. Although many drug-gene associations have been reported in the literature, the strength of evidence supporting each association… read more here.
Keywords: drug gene; drug; gene associations; pharmacogenetic testing ... See more keywords
Identifying Disease-Gene Associations With Graph-Regularized Manifold Learning
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2019.00270
Abstract: Complex diseases are known to be associated with disease genes. Uncovering disease-gene associations is critical for diagnosis, treatment, and prevention of diseases. Computational algorithms which effectively predict candidate disease-gene associations prior to experimental proof can… read more here.
Keywords: known associated; disease gene; disease; manifold learning ... See more keywords