High-Performance Multi-Dynamic Bond Cross-Linked Hydrogel with Spatiotemporal siRNA Delivery for Gene-Cell Combination Therapy of Intervertebral Disc Degeneration.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202206306
Abstract: Chronic inflammatory diseases, such as intervertebral disc degeneration (IVDD), which affect the lives of hundreds of millions of people, still lack effective and precise treatments. In this study, a novel hydrogel system with many extraordinary… read more here.
Keywords: cell; gene cell; cell combination; sirna ... See more keywords
An Implantable Double-Layered Spherical Scaffold Depositing Gene and Cell Agents to Facilitate Collaborative Cancer Immunotherapy.
Sign Up to like & getrecommendations! Published in 2025 at "ACS nano"
DOI: 10.1021/acsnano.5c01366
Abstract: Gene therapies and adoptive cell therapy (ACT) are promising strategies for cancer immunotherapy. Referring to their different mechanisms, the combination of these two might result in a strategy with potential collaborative and compensatory effects. However,… read more here.
Keywords: scaffold; cancer immunotherapy; cell; gene cell ... See more keywords
Imaging techniques: new avenues in cancer gene and cell therapy
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Gene Therapy"
DOI: 10.1038/cgt.2016.61
Abstract: Cancer is one of the world’s most concerning health problems and poses many challenges in the range of approaches associated with the treatment of cancer. Current understanding of this disease brings to the fore a… read more here.
Keywords: imaging techniques; cancer gene; cancer; gene ... See more keywords
Gene and cell therapy of human genetic diseases: Recent advances and future directions
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.70056
Abstract: Disruptions in normal development and the emergence of health conditions often result from the malfunction of vital genes in the human body. Decades of scientific research have focused on techniques to modify or substitute defective… read more here.
Keywords: cell therapy; genetic diseases; human genetic; gene cell ... See more keywords
Balancing benefits and burdens: a systematic review on ethical and social dimensions of gene and cell therapies for hereditary blood diseases
Sign Up to like & getrecommendations! Published in 2025 at "BMC Medical Ethics"
DOI: 10.1186/s12910-025-01188-3
Abstract: Sickle cell disease (SCD) and Diamond-Blackfan anemia syndrome (DBAS) are two hereditary blood diseases that present significant challenges to patients, their caregivers, and the healthcare system. Both conditions cause severe health complications and have limited… read more here.
Keywords: hereditary blood; cell therapies; cell; gene cell ... See more keywords
Still finding ways to augment the existing management of acute and chronic kidney diseases with targeted gene and cell therapies: Opportunities and hurdles
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2023.1143028
Abstract: The rising global incidence of acute and chronic kidney diseases has increased the demand for renal replacement therapy. This issue, compounded with the limited availability of viable kidneys for transplantation, has propelled the search for… read more here.
Keywords: kidney diseases; kidney; gene cell; chronic kidney ... See more keywords
Gene and Cell Therapy for Epilepsy: A Mini Review
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.868531
Abstract: Epilepsy is a chronic non-infectious disease of the brain, characterized primarily by recurrent unprovoked seizures, defined as an episode of disturbance of motor, sensory, autonomic, or mental functions resulting from excessive neuronal discharge. Despite the… read more here.
Keywords: therapy epilepsy; gene cell; cell therapy; therapy ... See more keywords
Editorial: Advanced (gene and cell) therapies for central nervous system applications
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2023.1140949
Abstract: The article Expression and Prognostic Role of Glia Maturation Factor- γ in Gliomas by Liu et al. investigated the role of glia maturation factor- γ (GMFG) in gliomas. Public datasets comprising 2,518 gliomas samples and… read more here.
Keywords: gmfg; editorial advanced; gene cell; gliomas ... See more keywords
Gene and Cell Therapy for Sarcomas: A Review
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DOI: 10.3390/cancers17071125
Abstract: Simple Summary In recent years, the number of FDA-approved gene and cell therapies for cancer has increased, albeit mostly for hematologic malignancies. This review focuses on gene and cell therapies for sarcomas that have been… read more here.
Keywords: sarcomas; gene; gene cell; cell therapy ... See more keywords