Exploring the Influence of Gene Networks on Driver Gene Classification
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Computational Biology"
DOI: 10.1089/cmb.2025.0043
Abstract: Cancer is a complex disease caused by mutations in the genome of cells. Genetic mutations can be divided into driver mutations, which are significant for the initiation and progression of cancer, and passenger mutations, which… read more here.
Keywords: networks driver; driver gene; gene classification; gene ... See more keywords
Supervised learning is an accurate method for network-based gene classification
Sign Up to like & getrecommendations! Published in 2020 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btaa150
Abstract: Abstract Background Assigning every human gene to specific functions, diseases and traits is a grand challenge in modern genetics. Key to addressing this challenge are computational methods, such as supervised learning and label propagation, that… read more here.
Keywords: gene classification; network based; supervised learning; network ... See more keywords
Identification of discriminant features from stationary pattern of nucleotide bases and their application to essential gene classification
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1154120
Abstract: Introduction: Essential genes are essential for the survival of various species. These genes are a family linked to critical cellular activities for species survival. These genes are coded for proteins that regulate central metabolism, gene… read more here.
Keywords: gene; essential gene; essential genes; gene classification ... See more keywords