CoFly: A gene coexpression database for the fruit fly Drosophila melanogaster.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21693
Abstract: The fruit fly Drosophila melanogaster can be used as a model organism for studying various problems in biomedicine and pest management. A large number of fruit fly transcriptomes have been profiled in various cell types,… read more here.
Keywords: fly drosophila; gene; gene coexpression; fruit fly ... See more keywords
Identification of vital modules and genes associated with heart failure based on weighted gene coexpression network analysis
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13827
Abstract: Heart failure (HF) is a chronic heart disease with a high incidence and mortality. Due to the regulatory complexity of gene coexpression networks, the underlying hub genes regulation in HF remain incompletely appreciated. We aimed… read more here.
Keywords: heart failure; gene coexpression; heart;
Identification of gene coexpression modules, hub genes, and pathways related to spinal cord injury using integrated bioinformatics methods
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27908
Abstract: Spinal cord injury (SCI) is characterized by dramatic neurons loss and axonal regeneration suppression. The underlying mechanism associated with SCI‐induced immune suppression is still unclear. Weighted gene coexpression network analysis (WGCNA) is now widely applied… read more here.
Keywords: gene coexpression; hub genes; modules hub; gene ... See more keywords
Weighted gene coexpression network analysis identifies specific transcriptional modules and hub genes related to intramuscular fat traits in chicken breast muscle
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28636
Abstract: Intramuscular fat (IMF) traits are important factors that influence meat quality. However, the molecular regulatory mechanisms that underlie this trait in chickens are still poorly understood at the gene coexpression level. Here, we performed a… read more here.
Keywords: intramuscular fat; analysis; hub genes; gene coexpression ... See more keywords
COXPRESdb v8: an animal gene coexpression database navigating from a global view to detailed investigations
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac983
Abstract: Abstract Gene coexpression is synchronization of gene expression across many cellular and environmental conditions and is widely used to infer the biological function of genes. Gene coexpression information is complex, comprising a complete graph of… read more here.
Keywords: coexpression; database; coxpresdb; gene coexpression ... See more keywords
Gene coexpression network analysis identifies hubs in hepatitis B virus–associated hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Chinese Medical Association"
DOI: 10.1097/jcma.0000000000000772
Abstract: Background: Hepatocellular carcinoma (HCC) is among the leading causes of cancer-related death worldwide. The molecular pathogenesis of HCC involves multiple signaling pathways. This study utilizes systems and bioinformatic approaches to investigate the pathogenesis of HCC.… read more here.
Keywords: network; gene coexpression; coexpression network; analysis ... See more keywords
Identification of Key Modules and Hub Genes of Keloids with Weighted Gene Coexpression Network Analysis
Sign Up to like & getrecommendations! Published in 2017 at "Plastic and Reconstructive Surgery"
DOI: 10.1097/prs.0000000000003014
Abstract: Background: Keloid scarring impairs patients’ quality of life, and although many therapeutic strategies have been developed, most remain unsatisfactory because of limited understanding of the mechanisms underlying keloid development. Methods: A microarray gene expression data… read more here.
Keywords: weighted gene; analysis; hub genes; gene coexpression ... See more keywords
Weighted gene coexpression network analysis reveals hub genes involved in cholangiocarcinoma progression and prognosis
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology Research"
DOI: 10.1111/hepr.13386
Abstract: Cholangiocarcinoma (CCA) is a highly malignant tumor found in the bile duct epithelial cells, and the second most common primary tumor of the liver. However, the pivotal roles of molecular biomarkers in oncogenesis of CCA… read more here.
Keywords: analysis reveals; weighted gene; gene coexpression; progression ... See more keywords
Gene Coexpression Connectivity Predicts Gene Targets Underlying High Ionic-Liquid Tolerance in Yarrowia lipolytica
Sign Up to like & getrecommendations! Published in 2022 at "mSystems"
DOI: 10.1128/msystems.00348-22
Abstract: Cellular robustness to cope with stressors is an important phenotype. Y. lipolytica is an industrial robust oleaginous yeast that has recently been discovered to tolerate record high concentrations of ILs, beneficial for novel biotransformation in… read more here.
Keywords: phenotype; coexpression connectivity; gene coexpression; lipolytica ... See more keywords
Identification of Key Genes in Severe Burns by Using Weighted Gene Coexpression Network Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/5220403
Abstract: The aims of this work were to explore the use of weighted gene coexpression network analysis (WGCNA) for identifying the key genes in severe burns and to provide a reference for finding therapeutic targets for… read more here.
Keywords: network; weighted gene; gene coexpression; coexpression network ... See more keywords
Crucial Genes in Aortic Dissection Identified by Weighted Gene Coexpression Network Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/7585149
Abstract: Background Aortic dissection (AD) is a lethal vascular disease with high mortality and morbidity. Though AD clinical pathology is well understood, its molecular mechanisms remain unclear. Specifically, gene expression profiling helps illustrate the potential mechanism… read more here.
Keywords: gene; analysis; aortic dissection; gene coexpression ... See more keywords