RAG Deficiency: Two Genes, Many Diseases
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-018-0537-4
Abstract: PurposeTo review the clinical and laboratory spectrum of RAG gene defects in humans, and discuss the mechanisms underlying phenotypic heterogeneity, the basis of immune dysregulation, and the current and perspective treatment modalities.MethodsLiterature review and analysis… read more here.
Keywords: treatment; rag deficiency; defects humans; gene defects ... See more keywords
The molecular immunology of human susceptibility to fungal diseases: lessons from single gene defects of immunity
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2019.1584038
Abstract: ABSTRACT Introduction: Fungal diseases are a threat to human health. Therapies targeting the fungus continue to lead to disappointing results. Strategies targeting the host response represent unexplored opportunities for innovative treatments. To do so rationally… read more here.
Keywords: gene defects; susceptibility; immunology; single gene ... See more keywords