Abstract 2062: Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry
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DOI: 10.1158/1538-7445.am2018-2062
Abstract: Childhood neuroblastomas with MYCN gene amplification form a particularly high-risk subset of this disease and are difficult to treat effectively. This has focused attention on tumor-specific gene dependencies that reflect important pathways in tumorigenesis, and… read more here.
Keywords: regulatory circuitry; gene dependencies; mycn amplified; amplified neuroblastoma ... See more keywords