CRISPR/Cas9-Based Gene Dropout Screens.
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DOI: 10.1007/978-1-4939-8876-1_15
Abstract: Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9-based technology enables efficient and precise perturbations of target genomic sites. Combining the endonuclease Cas9 and a pooled guide RNA library allows for systematic screenings of genes associated with… read more here.
Keywords: cas9 based; crispr cas9; gene dropout; dropout screens ... See more keywords