Clock Gene Dysregulation Induced by Chronic ER Stress Disrupts β-cell Function
Sign Up to like & getrecommendations! Published in 2017 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2017.03.040
Abstract: In Wfs1−/−Ay/a islets, in association with endoplasmic reticulum (ER) stress, D-site-binding protein (Dbp) expression decreased and Nuclear Factor IL-3 (Nfil3)/E4 Promoter-binding protein 4 (E4bp4) expression increased, leading to reduced DBP transcriptional activity. Similar alterations were… read more here.
Keywords: clock gene; gene dysregulation; stress; gene ... See more keywords
Maternal and Fetal Mitochondrial Gene Dysregulation in Hypertensive Disorders of Pregnancy.
Sign Up to like & getrecommendations! Published in 2023 at "Physiological genomics"
DOI: 10.1152/physiolgenomics.00005.2023
Abstract: Mitochondrial dysfunction has been implicated in pregnancy-induced hypertension (PIH). The role of mitochondrial gene dysregulation in PIH, and consequences for maternal-fetal interactions, remain elusive. Here, we investigated mitochondrial gene expression and dysregulation in maternal and… read more here.
Keywords: mitochondrial gene; gene dysregulation; maternal fetal; fetal mitochondrial ... See more keywords