Study Essential Gene Functions by Plasmid Shuffling.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0868-5_5
Abstract: An essential gene is defined as a gene that cannot be completely removed from the genome. Investigation of an essential gene function is limited because its deletion strain cannot be readily created. Here we describe… read more here.
Keywords: plasmid shuffling; study essential; essential gene; gene ... See more keywords
Prediction of optimal gene functions for osteosarcoma using network-based- guilt by association method based on gene oncology and microarray profile.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of bone oncology"
DOI: 10.1016/j.jbo.2017.04.003
Abstract: In the current study, we planned to predict the optimal gene functions for osteosarcoma (OS) by integrating network-based method with guilt by association (GBA) principle (called as network-based gene function inference approach) based on gene… read more here.
Keywords: network based; optimal gene; gene; oncology ... See more keywords
MicroScope: an integrated platform for the annotation and exploration of microbial gene functions through genomic, pangenomic and metabolic comparative analysis
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz926
Abstract: Abstract Large-scale genome sequencing and the increasingly massive use of high-throughput approaches produce a vast amount of new information that completely transforms our understanding of thousands of microbial species. However, despite the development of powerful… read more here.
Keywords: microscope; analysis; annotation; gene functions ... See more keywords
A mechanism of gene evolution generating mucin function
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abm8757
Abstract: How novel gene functions evolve is a fundamental question in biology. Mucin proteins, a functionally but not evolutionarily defined group of proteins, allow the study of convergent evolution of gene function. By analyzing the genomic… read more here.
Keywords: gene functions; mechanism gene; mucin function; gene ... See more keywords
Abstract 4538: UniConSig: A new algorithm for genome wide quantification of gene functions and disease associations
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-4538
Abstract: One of the greatest hurdles for cancer biologists is to identify the cancer-causal genes from thousands of candidate genes suggested by large-scale genomics or deep sequencing studies. In our previous study, we discovered that cancer… read more here.
Keywords: concept; genome wide; wide quantification; cancer ... See more keywords
Parallel selection on ecologically relevant gene functions in the transcriptomes of highly diversifying salmonids
Sign Up to like & getrecommendations! Published in 2019 at "BMC Genomics"
DOI: 10.1186/s12864-019-6361-2
Abstract: BackgroundSalmonid fishes are characterised by a very high level of variation in trophic, ecological, physiological, and life history adaptations. Some salmonid taxa show exceptional potential for fast, within-lake diversification into morphologically and ecologically distinct variants,… read more here.
Keywords: diversifying selection; ontology; selection; gene ... See more keywords
Auxiliary Metabolic Gene Functions in Pelagic and Benthic Viruses of the Baltic Sea
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.863620
Abstract: Marine microbial communities are facing various ecosystem fluctuations (e.g., temperature, organic matter concentration, salinity, or redox regimes) and thus have to be highly adaptive. This might be supported by the acquisition of auxiliary metabolic genes… read more here.
Keywords: gene functions; auxiliary metabolic; metabolic gene; baltic sea ... See more keywords