An Eight-Gene Hypoxia Signature Predicts Survival in Pancreatic Cancer and Is Associated With an Immunosuppressed Tumor Microenvironment
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DOI: 10.3389/fimmu.2021.680435
Abstract: Intratumoral hypoxia is a widely established element of the pancreatic tumor microenvironment (TME) promoting immune escape, tumor invasion, and progression, while contributing to treatment resistance and poor survival. Despite this critical role, hypoxia is underrepresented… read more here.
Keywords: gene hypoxia; eight gene; signature; hypoxia signature ... See more keywords