Breast cancer radioresistance may be overcome by osteopontin gene knocking out with CRISPR/Cas9 technique.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique"
DOI: 10.1016/j.canrad.2020.08.048
Abstract: PURPOSE Osteopontin (OPN) is a phosphoglycoprotein, with a wide range of physiological and pathological roles. High expression of OPN promotes aggressive behavior, causes poor prognosis in tumor cells, and reduces the survival of patients. Since… read more here.
Keywords: crispr cas9; radioresistance; gene knocking; gene ... See more keywords