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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2206938119
Abstract: Significance In a human cell, transcription of a particular gene invariably fluctuates with time, and the fluctuations of several transcripts can be correlated because they are regulated by the same transcription factor. By developing a…
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Keywords:
correlated gene;
cell;
gene modules;
single cell ... See more keywords
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Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac088
Abstract: MOTIVATION Advanced deep learning techniques have been widely applied in disease diagnosis and prognosis with clinical omics, especially gene expression data. In the regulation of biological processes and disease progression, genes often work interactively rather…
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Keywords:
diagnosis prognosis;
multi level;
gene modules;
graph ... See more keywords
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Published in 2022 at "International Journal of Genomics"
DOI: 10.1155/2022/7471063
Abstract: Somatic embryogenesis (SE), which occurs naturally in many plant species, serves as a model to elucidate cellular and molecular mechanisms of embryo patterning in plants. Decoding the regulatory landscape of SE is essential for its…
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Keywords:
hub genes;
embryogenesis;
gene modules;
analysis ... See more keywords
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Published in 2017 at "Translational cancer research"
DOI: 10.21037/13780
Abstract: Background: Bone metastases are a cancer which causes great injury to people world-widely. Although gene expression analyses had been performed previously, systemic co-expression analysis for this cancer is still lacking. Methods: Here, we analyzed the…
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Keywords:
gene modules;
bone metastases;
expression;
expression analysis ... See more keywords
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Published in 2018 at "OncoTargets and therapy"
DOI: 10.2147/ott.s163891
Abstract: Introduction Colorectal cancer (CRC) is the fourth most common cause of cancer-related mortality worldwide. The tumor, node, metastasis (TNM) stage remains the standard for CRC prognostication. Identification of meaningful microRNA (miRNA) and gene modules or…
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Keywords:
gene modules;
pathological stage;
mirna gene;
cancer ... See more keywords
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Published in 2019 at "Genes"
DOI: 10.3390/genes10020121
Abstract: Melatonin, the hormone of darkness, is a peculiar molecule found in most living organisms. Emerging as a potent broad-spectrum antioxidant, melatonin was repurposed into extra roles such as the modulation of circadian and seasonal rhythmicity,…
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Keywords:
gene modules;
behavior parallels;
melatonin;
singularity cetacea ... See more keywords
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Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20163846
Abstract: Allelopathy is a central process in crop–weed interactions and is mediated by the release of allelochemicals that result in adverse growth effects on one or the other plant in the interaction. The genomic mechanism for…
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Keywords:
gene modules;
rice barnyardgrass;
biosynthetic gene;
gene clusters ... See more keywords