The gene mutational discrepancies between primary and paired metastatic colorectal carcinoma detected by next-generation sequencing
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-018-2742-1
Abstract: PurposeTo better understand the gene mutational status and heterogeneity between primary and metastatic CRC (mCRC) using a sensitive sequencing method.MethodsThe mutational status of EGFR, KRAS, NRAS, PIK3CA, ERBB2, BRAF, KIT, and PDGFRA was analyzed in… read more here.
Keywords: gene mutational; primary paired; mutational status; gene ... See more keywords
Gene mutational pattern and expression level in 560 acute myeloid leukemia patients and their clinical relevance
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-017-1279-4
Abstract: BackgroundCytogenetic aberrations and gene mutations have long been regarded as independent prognostic markers in AML, both of which can lead to misexpression of some key genes related to hematopoiesis. It is believed that the expression… read more here.
Keywords: expression level; aml; expression; gene mutational ... See more keywords