Identification of a novel gene pairs signature in the prognosis of gastric cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1303
Abstract: Current prognostic signatures need to be improved in identifying high‐risk patients of gastric cancer (GC). Thus, we aimed to develop a reliable prognostic signature that could assess the prognosis risk in GC patients. Two microarray… read more here.
Keywords: risk; prognosis; signature; cancer ... See more keywords
Signature based on metabolic‐related gene pairs can predict overall survival of osteosarcoma patients
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DOI: 10.1002/cam4.3984
Abstract: Osteosarcoma is a tumour of malignant origin in children and adolescents. Recent progression indicates that it is necessary to develop new therapies to improve the patient's prognosis rather than strengthen anti‐tumour chemotherapy. Researchers recently realised… read more here.
Keywords: related gene; signature based; metabolic related; based metabolic ... See more keywords
Four differentially methylated gene pairs to predict the prognosis for early stage hepatocellular carcinoma patients
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26256
Abstract: Hepatocellular carcinoma (HCC) was the second most common malignant tumor with a poor prognostic condition. We aimed to identify novel methylation signatures to predict HCC patients at their early stages. Differentially expressed methylated genes between… read more here.
Keywords: hepatocellular carcinoma; hcc; hcc patients; differentially methylated ... See more keywords
Identification of CD28 and PTEN as novel prognostic markers for cervical cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27453
Abstract: Cervical cancer (CC) is the most common malignant tumor with poor clinical outcome among women. Identification of novel biomarkers could be beneficial for the clinical diagnosis and treatment of CC. This study aimed to identify… read more here.
Keywords: methylation; cervical cancer; cancer; gene pairs ... See more keywords
Identifying digenic disease genes via machine learning in the Undiagnosed Diseases Network.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2021.08.010
Abstract: Rare diseases affect millions of people worldwide, and discovering their genetic causes is challenging. More than half of the individuals analyzed by the Undiagnosed Diseases Network (UDN) remain undiagnosed. The central hypothesis of this work… read more here.
Keywords: diseases network; gene pairs; undiagnosed diseases; gene ... See more keywords
GeneCoNet: A web application server for constructing cancer patient-specific gene correlation networks with prognostic gene pairs.
Sign Up to like & getrecommendations! Published in 2021 at "Computer methods and programs in biomedicine"
DOI: 10.1016/j.cmpb.2021.106465
Abstract: BACKGROUND AND OBJECTIVE Most prognostic gene signatures that have been known for cancer are either individual genes or combination of genes. Both individual genes and combination of genes do not provide information on gene-gene relations,… read more here.
Keywords: gene pairs; gene correlation; cancer; prognostic gene ... See more keywords
A novel tailored immune gene pairs signature for overall survival prediction in lower-grade gliomas
Sign Up to like & getrecommendations! Published in 2021 at "Translational Oncology"
DOI: 10.1016/j.tranon.2021.101109
Abstract: Highlights • The Immune-related gene pairs (IRGPs) pronostic signature for LGG is correlated with immune cells infiltration.• WGCNA presented a gene set correlating with immune cells infiltration and genes co-expression relationships were visualized.• The nomogram… read more here.
Keywords: tailored immune; gene pairs; novel tailored; immune gene ... See more keywords
A qualitative transcriptional signature for determining the grade of colorectal adenocarcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Gene Therapy"
DOI: 10.1038/s41417-019-0139-1
Abstract: Histological grading (HG) is an important prognostic factor of colorectal adenocarcinoma (CRAC): the high-grade CRAC patients have poorer prognosis after tumor resection. Especially, the high-grade stage II CRAC patients are recommended to receive adjuvant chemotherapy.… read more here.
Keywords: high grade; grade; crac; gene pairs ... See more keywords
Translational coupling via termination-reinitiation in archaea and bacteria
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-11999-9
Abstract: The genomes of many prokaryotes contain substantial fractions of gene pairs with overlapping stop and start codons (ATGA or TGATG). A potential benefit of overlapping gene pairs is translational coupling. In 720 genomes of archaea… read more here.
Keywords: gene pairs; reinitiation; overlapping gene; archaea bacteria ... See more keywords
The Essentiality Status of Mouse Duplicate Gene Pairs Correlates with Developmental Co-Expression Patterns
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DOI: 10.1038/s41598-019-39894-9
Abstract: During the evolution of multicellular eukaryotes, gene duplication occurs frequently to generate new genes and/or functions. A duplicated gene may have a similar function to its ancestral gene. Therefore, it may be expected that duplicated… read more here.
Keywords: gene pairs; expression patterns; expression; duplicate gene ... See more keywords
A signature of 13 autophagy‑related gene pairs predicts prognosis in hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1880084
Abstract: Growing evidences suggest that autophagy plays a momentous part in the tumorigenesis and development of hepatocellular carcinoma (HCC). However, there are not many researches to predict the prognosis of HCC using autophagy-related genes. Therefore, based… read more here.
Keywords: autophagy related; related gene; autophagy; signature ... See more keywords