Articles with "gene polymorphism" as a keyword



Association of Lp‐PLA2 G994T gene polymorphism with risk of ischemic stroke in Chinese population

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Published in 2017 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.21999

Abstract: The association between lipoprotein‐associated phospholipase A2 (Lp‐PLA2) G994T gene polymorphism and the risk of ischemic stroke is unclear. The aim of this study is to investigate the influence of Lp‐PLA2 G994T genetic variant on the… read more here.

Keywords: g994t gene; ischemic stroke; gene polymorphism; pla2 g994t ... See more keywords
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Association of interleukin‐18 gene polymorphism and its protein expression with the lower extremity deep venous thrombosis in the chinese han population: A case‐control study

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Published in 2018 at "Journal of Clinical Laboratory Analysis"

DOI: 10.1002/jcla.22345

Abstract: We aim to explain the correlation among IL‐18 gene polymorphism, its protein expression and LEDVT in the Chinese Han population. read more here.

Keywords: protein expression; gene polymorphism; chinese han; polymorphism protein ... See more keywords
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Interleukin‐21 receptor gene polymorphism is associated with hepatitis B virus‐related hepatocellular carcinoma in Chinese patients

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Published in 2019 at "Journal of Clinical Laboratory Analysis"

DOI: 10.1002/jcla.22860

Abstract: We investigated the relationship between hepatitis B virus (HBV)‐related pathogenesis and single nucleotide polymorphisms (SNPs) in interleukin‐21 (IL‐21)‐JAK‐STAT signaling pathway genes. read more here.

Keywords: gene polymorphism; hepatitis; hepatitis virus; receptor gene ... See more keywords
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Potential role of glutathione S-transferase P1 gene polymorphism and metabolic syndrome in lower urinary tract symptoms attributed to benign prostatic hyperplasia

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Published in 2021 at "World Journal of Urology"

DOI: 10.1007/s00345-021-03778-3

Abstract: The aim of the study is to investigate the effects of glutathione S-transferase P1 (GSTP1) gene polymorphism and metabolic syndrome (MS) on lower urinary tract symptoms (LUTS) attributed to benign prostatic hyperplasia (BPH). This study… read more here.

Keywords: gene polymorphism; benign prostatic; group; bph ... See more keywords
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Klotho G-395A gene polymorphism: impact on progression of end-stage renal disease and development of cardiovascular complications in children on dialysis

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Published in 2017 at "Pediatric Nephrology"

DOI: 10.1007/s00467-017-3877-z

Abstract: BackgroundKlotho G-395-A gene polymorphism may impact children with end-stage renal disease (ESRD). We investigated the relevance of Klotho G-395-A on ESRD development and progression, and its relationship with evolution of cardiovascular complications in pediatric dialysis… read more here.

Keywords: cardiovascular complications; gene polymorphism; development; disease ... See more keywords
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Interleukin-6-572 promoter gene polymorphism and its association with chronic hepatitis C-induced hepatocellular carcinoma: an Egyptian study

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Published in 2017 at "Comparative Clinical Pathology"

DOI: 10.1007/s00580-017-2571-7

Abstract: Hepatocellular carcinoma (HCC) is the most common type of liver cancer, where the risk of its development is always multifactorial. Human interleukin-6 (IL-6) is a pro-inflammatory cytokine that plays a crucial role in the regulation… read more here.

Keywords: hepatocellular carcinoma; gene polymorphism; study; gene ... See more keywords
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Leptin receptor gene (A/G) polymorphism rs1137101 and renal cell carcinoma

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Published in 2018 at "Molecular and Cellular Biochemistry"

DOI: 10.1007/s11010-018-3320-1

Abstract: Leptin plays an important role in carcinogenesis as leptin/leptin receptor signaling promotes the angiogenesis, proliferation, and inhibits epithelial cell apoptosis. Variants in the leptin receptor gene have potential associations with renal cell carcinoma (RCC). We… read more here.

Keywords: gene; gene polymorphism; leptin receptor; polymorphism ... See more keywords
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Type 2 diabetes mellitus and TCF7L2 gene rs12255372 G/T polymorphism: a meta-analysis involving 7990 subjects

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Published in 2017 at "International Journal of Diabetes in Developing Countries"

DOI: 10.1007/s13410-017-0560-7

Abstract: The transcription factor 7-like 2 (TCF7L2) G/T gene polymorphism, also known as rs12255372, has been linked to increases in risk for type 2 diabetes (T2DM), especially in the European population. However, a clear consensus on… read more here.

Keywords: tcf7l2 gene; gene polymorphism; chinese population; gene ... See more keywords
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The role and mechanism of CARD9 gene polymorphism in diseases.

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Published in 2020 at "Biomedical journal"

DOI: 10.1016/j.bj.2020.12.006

Abstract: CARD9 is a cytosolic adaptor in myeloid cells, has a critical role in inflammatory disorders, and provides a protective function against microbial pathogen, especially fungal infection. Recently, CARD9 polymorphisms are of interest, showing a positive… read more here.

Keywords: gene polymorphism; role mechanism; card9 polymorphisms; role ... See more keywords
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APOE gene polymorphism alters cerebral oxygen saturation and quantitative EEG in early-stage traumatic brain injury

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Published in 2022 at "Clinical Neurophysiology"

DOI: 10.1016/j.clinph.2022.01.131

Abstract: OBJECTIVE To investigate the influence of apolipoprotein E (APOE) gene polymorphism on regional cerebral oxygen saturation (rScO2) and quantitative electroencephalogram (QEEG) at the early phase of adult traumatic brain injury (TBI). METHODS clinical data of… read more here.

Keywords: apoe gene; tbi; gene polymorphism; early stage ... See more keywords
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AR C-106T gene polymorphism and diabetic nephropathy in the Eastern Asians with T2DM: A meta-analysis including 2120 subjects.

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Published in 2017 at "Diabetes research and clinical practice"

DOI: 10.1016/j.diabres.2017.06.014

Abstract: BACKGROUND Aldose reductase (AR) gene C-106T polymorphism may be associated with diabetic nephropathy (DN) susceptibility, but the results of individual studies remain controversial. OBJECTIVE AND METHODS To explore the relationship between AR gene C-106T gene… read more here.

Keywords: gene polymorphism; 106t gene; eastern asians; gene 106t ... See more keywords