Method for functional analysis of a gene of interest in Streptococcus mutans: gene disruption followed by purification of a polyhistidine-tagged gene product.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2018.11.010
Abstract: Typical methods for elucidating the function of a particular gene involve comparative phenotypic analysis of the wild-type strain and a strain in which the gene of interest has been disrupted. We previously described a simple… read more here.
Keywords: gene product; gene disruption; product; purification ... See more keywords
Structural Basis for the Interactions of the Colibactin Resistance Gene Product ClbS with DNA.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemistry"
DOI: 10.1021/acs.biochem.1c00201
Abstract: The natural product colibactin, along with its associated biosynthetic gene cluster, is an example system for the role microbially derived small molecules play in the human microbiome. This is particularly relevant in the human gut,… read more here.
Keywords: gene product; dna; clbs; product clbs ... See more keywords
Genetic screening for monogenic hypertension in hypertensive individuals in a clinical setting
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Genetics"
DOI: 10.1136/jmedgenet-2019-106145
Abstract: Background Monogenic hypertension describe a series of hypertensive syndromes that are inherited by Mendelian laws. Sometimes genetic testing is required to provide evidence for their diagnoses, precise classification and targeted treatment. This study is the… read more here.
Keywords: product expression; gene product; monogenic hypertension; hypertension ... See more keywords
The prognostic implications of growth-related gene product β in laryngeal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Oncology Letters"
DOI: 10.3892/ol.2017.6604
Abstract: Growth-related gene product β (GROβ) is an angiogenic chemokine that belongs to the CXC chemokine family, and a number of studies have suggested that GROβ is associated with tumor development and progression. However, a number… read more here.
Keywords: related gene; gene product; expression; gro ... See more keywords