Articles with "gene rearrangement" as a keyword



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Massive gene rearrangement in mitogenomes of phytoseiid mites.

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Published in 2021 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2021.07.011

Abstract: Mitochondrial (mt) gene sequences have been widely used to infer phylogeny in animals. The relative order of mt genes in the mitogenome can also be a useful marker for evolution, but the propensity of mt… read more here.

Keywords: phytoseiid mites; order; gene rearrangement; family ... See more keywords
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Single-molecule long-read transcriptome profiling of Platysternon megacephalum mitochondrial genome with gene rearrangement and control region duplication

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Published in 2018 at "RNA Biology"

DOI: 10.1080/15476286.2018.1521212

Abstract: ABSTRACT Platysternon megacephalum is the sole living representative of the poorly studied turtle lineage Platysternidae. Their mitochondrial genome has been subject to gene rearrangement and control region duplication, resulting in a unique mitochondrial gene order… read more here.

Keywords: gene rearrangement; control region; rearrangement control; mitochondrial genome ... See more keywords
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Mechanism of bacterial gene rearrangement: SprA-catalyzed precise DNA recombination and its directionality control by SprB ensure the gene rearrangement and stable expression of spsM during sporulation in Bacillus subtilis

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Published in 2017 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkx466

Abstract: Abstract A sporulation-specific gene, spsM, is disrupted by an active prophage, SPβ, in the genome of Bacillus subtilis. SPβ excision is required for two critical steps: the onset of the phage lytic cycle and the… read more here.

Keywords: sporulation; gene rearrangement; spsm; recombination ... See more keywords
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Dramatic response to crizotinib in a breast cancer patient with ALK gene rearrangement.

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Published in 2022 at "Anti-cancer drugs"

DOI: 10.1097/cad.0000000000001272

Abstract: Rearrangements of the anaplastic lymphoma kinase (ALK) gene are present in 3-5% of non-small-cell lung cancer (NSCLC), while it was 0.2% in NSCLC tumors. Due to its low frequency, it is extremely challenging to conduct… read more here.

Keywords: gene rearrangement; breast cancer; alk gene; alk ... See more keywords
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Cutaneous myoepithelioma with EWSR1 gene rearrangement and its differentials: A diagnostic challenge.

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Published in 2023 at "Journal of cutaneous pathology"

DOI: 10.1111/cup.14433

Abstract: Cutaneous myoepithelioma is a rare benign soft tissue neoplasm of myoepithelial cells involving the skin and subcutis. These tumors can be diagnostically challenging. The plasticity of myoepithelial cells leads to wide variability in the cytomorphology,… read more here.

Keywords: gene rearrangement; ewsr1 gene; rearrangement differentials; myoepithelioma ewsr1 ... See more keywords
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Assessment of ALK gene rearrangement in lung cancer using a new rapid automated SureFISH (Dako Omnis) assay

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Published in 2017 at "Journal of Clinical Pathology"

DOI: 10.1136/jclinpath-2016-204311

Abstract: The ALK fluorescence in situ hybridisation (FISH) method is the examination essential for pathological diagnosis and choice of molecular-targeted therapy in ALK-rearranged lung cancer. Here, for detection of ALK gene rearrangement in patients with lung… read more here.

Keywords: alk; gene rearrangement; dako omnis; lung cancer ... See more keywords
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Detection of ALK Gene Rearrangement in Cell-free RNA from Lung Cancer Malignant Pleural Effusion

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Published in 2020 at "BioMed Research International"

DOI: 10.1155/2020/6124106

Abstract: The aim of this study was to evaluate the feasibility of measuring ALK gene rearrangement in cell-free RNA (cf-RNA) of the supernatant from malignant pleural effusion (MPE). Supernatant, cell blocks, and matched sera samples were… read more here.

Keywords: gene rearrangement; cell; rna; alk gene ... See more keywords
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Novel gene rearrangement in the mitochondrial genome of Siliqua minima (Bivalvia, Adapedonta) and phylogenetic implications for Imparidentia

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Published in 2021 at "PLoS ONE"

DOI: 10.1371/journal.pone.0249446

Abstract: Siliqua minima (Gmelin, 1791) is an important economic shellfish species belonging to the family Pharidae. To date, the complete mitochondrial genome of only one species in this family (Sinonovacula constricta) has been sequenced. Research on… read more here.

Keywords: gene rearrangement; minima; siliqua minima; mitochondrial genome ... See more keywords
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PD-1/PD-L1 inhibitor activity in patients with gene-rearrangement positive non-small cell lung cancer—an IMMUNOTARGET case series

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Published in 2022 at "Translational Lung Cancer Research"

DOI: 10.21037/tlcr-22-329

Abstract: Background Prior IMMUNOTARGET registry data had suggested that responses to immune [anti PD(L)1] monotherapy in gene-arranged non-small cell lung cancer (NSCLC) were rare or absent, depending on the specific oncogene. Methods IMMUNOTARGET sites reporting prior… read more here.

Keywords: gene rearrangement; lung cancer; gene; non small ... See more keywords
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First Report on Mitochondrial Gene Rearrangement in Non-Biting Midges, Revealing a Synapomorphy in Stenochironomus Kieffer (Diptera: Chironomidae)

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Published in 2022 at "Insects"

DOI: 10.3390/insects13020115

Abstract: Simple Summary Gene rearrangement is an additional type of data to support relationships of taxa, with rearrangement synapomorphies identified across multiple orders and at many different taxonomic levels. The concept to use mitochondrial gene rearrangements… read more here.

Keywords: mitochondrial gene; gene; gene rearrangement; chironomidae ... See more keywords
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Positive Correlation of the Gene Rearrangements and Evolutionary Rates in the Mitochondrial Genomes of Thrips (Insecta: Thysanoptera)

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Published in 2022 at "Insects"

DOI: 10.3390/insects13070585

Abstract: Simple Summary Aeolothrips, commonly known as banded thrips, is the largest genus of the family Aeolothripidae (predatory thrips). In the current study, we sequenced the mitochondrial genome (mitogenome) of the banded thrip species Aeolothrips xinjiangensis.… read more here.

Keywords: gene rearrangement; thysanoptera; mitogenomes thrips; correlation ... See more keywords