Association of Body Mass Index With 21-Gene Recurrence Score Among Women With Estrogen Receptor–Positive, ERBB2–Negative Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.43935
Abstract: Key Points Question Is high body mass index (BMI) a factor associated with a high 21-gene recurrence score in estrogen receptor (ER)–positive, ERBB2-negative (formerly HER2 or HER2/neu) breast cancer, especially in younger patients (≤45 years)… read more here.
Keywords: recurrence score; breast cancer; cancer; gene recurrence ... See more keywords
Association of Neighborhood-Level Household Income With 21-Gene Recurrence Score and Survival Among Patients With Estrogen Receptor–Positive Breast Cancer
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.0179
Abstract: Key Points Question Do household income levels factor into 21-gene recurrence score (RS) and mortality among patients with estrogen receptor (ER)-positive breast cancer? Findings In this cohort study involving 119 478 women, low income was associated… read more here.
Keywords: household income; recurrence score; patients estrogen; gene recurrence ... See more keywords
Associations between use of the 21‐gene recurrence score assay and chemotherapy regimen selection in a statewide registry
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DOI: 10.1002/cncr.30429
Abstract: The 21‐gene recurrence score (RS) assay predicts response to adjuvant chemotherapy in patients with early‐stage, hormone receptor‐positive, human epidermal growth factor receptor 2 (HER2)‐negative invasive breast cancer, but to the authors' knowledge, the role of… read more here.
Keywords: chemotherapy; chemotherapy regimen; gene recurrence; recurrence score ... See more keywords
Impact of TAILORx on chemotherapy prescribing and 21‐gene recurrence score–guided treatment costs in a population‐based cohort of patients with breast cancer
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DOI: 10.1002/cncr.33982
Abstract: The trial assigning individualized options for treatment (Rx) (TAILORx) confirmed the predictive value of the 21‐gene recurrence score (RS) assay in hormone receptor (HR)–positive, HER2‐negative, node‐negative breast cancer and established thresholds for chemotherapy benefit in… read more here.
Keywords: cancer; breast cancer; guided treatment; treatment ... See more keywords
21‐Gene Recurrence Score Testing in HER2‐positive Patients
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DOI: 10.1016/j.clbc.2018.11.011
Abstract: Introduction: The 21‐gene recurrence score (RS) has been extensively studied and validated in patients with estrogen receptor‐positive (ER+), human epidermal growth factor 2 (HER2)‐negative breast cancer; however, RS testing is not routinely performed in patients… read more here.
Keywords: her2; risk; gene recurrence; breast cancer ... See more keywords
Evaluation oncotype DX® 21‐gene recurrence score and clinicopathological parameters: a single institutional experience
Sign Up to like & getrecommendations! Published in 2023 at "Histopathology"
DOI: 10.1111/his.14863
Abstract: Oncotype DX recurrence score (RS) is a clinically validated assay, which predicts the likelihood of disease recurrence in oestrogen receptor‐positive/HER2‐negative (ER+/HER2−) breast cancer (BC). In this study we aimed to compare the performance of Oncotype… read more here.
Keywords: clinicopathological parameters; oncotype gene; recurrence score; recurrence ... See more keywords
Abstract P1-09-14: Breast carcinoma with 21-gene recurrence score lower than 18: Rate of distant metastases in a large series with clinical follow-up
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs16-p1-09-14
Abstract: Background: The 21-gene recurrence score (RS) estimates the likelihood of distant recurrence and the benefit from chemotherapy in patients with early-stage node-negative, estrogen receptor (ER)-positive, HER2-negative breast carcinoma. The use of the assay resulted in… read more here.
Keywords: gene recurrence; breast; breast cancer; recurrence score ... See more keywords
Abstract PD7-05: How 21-gene recurrence score assay is being used to individualize adjuvant chemotherapy recommendations in ER+/HER2 -node positive breast cancer -A national cancer data base study
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs16-pd7-05
Abstract: Introduction: The 21-gene Recurrence Score (RS) assay has been shown in retrospective studies to predict benefit of adjuvant chemotherapy (AC) in node positive (N+) breast cancer (BC) patients (pts). This study evaluates the trends and… read more here.
Keywords: gene recurrence; breast cancer; recurrence score; cancer ... See more keywords
Comparison of the Modified Immunohistochemical Marker Score and 21-Gene Recurrence Score Assay in Patients with Estrogen Receptor-Positive Breast Cancer
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DOI: 10.1159/000521287
Abstract: Introduction: Not only the 21-gene recurrence score (RS) assay but also online prognostic tools and immunohistochemical prognostic models predict chemotherapy benefits for women with early breast cancer (BC). Multigene assays, including Oncotype DX, are expensive… read more here.
Keywords: breast cancer; patients estrogen; score; recurrence score ... See more keywords
The 21-Gene Recurrence Score Assay and Prediction of Chemotherapy Benefit: A Propensity Score-Matched Analysis of the SEER Database
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DOI: 10.3390/cancers12071829
Abstract: Background: To evaluate the performance of the 21-gene recurrence score (RS) assay in predicting chemotherapy benefit in the Surveillance, Epidemiology, and End Results population, we aimed to assess breast cancer-specific mortality (BCSM) by chemotherapy use… read more here.
Keywords: chemotherapy benefit; analysis; benefit; gene recurrence ... See more keywords