Signatures of Convergent Evolution and Natural Selection at the Alcohol Dehydrogenase Gene Region are Correlated with Agriculture in Ethnically Diverse Africans
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msac183
Abstract: Abstract The alcohol dehydrogenase (ADH) family of genes encodes enzymes that catalyze the metabolism of ethanol into acetaldehyde. Nucleotide variation in ADH genes can affect the catalytic properties of these enzymes and is associated with… read more here.
Keywords: alcohol dehydrogenase; agriculture; gene region; gene ... See more keywords
Simulation Research on the Methods of Multi-Gene Region Association Analysis Based on a Functional Linear Model
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13030455
Abstract: Genome-wide association analysis is an important approach to identify genetic variants associated with complex traits. Complex traits are not only affected by single gene loci, but also by the interaction of multiple gene loci. Studies… read more here.
Keywords: association analysis; multi gene; gene; gene region ... See more keywords
[The Mutations on embA, embB and embC Gene Region in Ethambutol-Resistant and Susceptible Clinical Mycobacterium tuberculosis Complex Isolates].
Sign Up to like & getrecommendations! Published in 2023 at "Mikrobiyoloji bulteni"
DOI: 10.5578/mb.20239904
Abstract: Ethambutol (EMB) is one of the first-line drugs used in the standard combination therapy for tuberculosis (TB) caused by Mycobacterium tuberculosis complex (MTC), and resistance to drugs that play a key role in treatment is… read more here.
Keywords: embc gene; emb; resistance; gene region ... See more keywords