Silence as a way of niche adaptation: mecC-MRSA with variations in the accessory gene regulator (agr) functionality express kaleidoscopic phenotypes
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-71640-4
Abstract: Functionality of the accessory gene regulator (agr) quorum sensing system is an important factor promoting either acute or chronic infections by the notorious opportunistic human and veterinary pathogen Staphylococcus aureus. Spontaneous alterations of the agr… read more here.
Keywords: functionality; agr functionality; gene regulator; mrsa ... See more keywords
RegEnrich gene regulator enrichment analysis reveals a key role of the ETS transcription factor family in interferon signaling
Sign Up to like & getrecommendations! Published in 2022 at "Communications Biology"
DOI: 10.1038/s42003-021-02991-5
Abstract: Changes in a few key transcriptional regulators can lead to different biological states. Extracting the key gene regulators governing a biological state allows us to gain mechanistic insights. Most current tools perform pathway/GO enrichment analysis… read more here.
Keywords: analysis; expression; enrichment analysis; ets transcription ... See more keywords