A global evolutionary and metabolic analysis of human obesity gene risk variants.
Sign Up to like & getrecommendations! Published in 2017 at "Gene"
DOI: 10.1016/j.gene.2017.07.002
Abstract: It is generally accepted that the selection of gene variants during human evolution optimized energy metabolism that now interacts with our obesogenic environment to increase the prevalence of obesity. The purpose of this study was… read more here.
Keywords: obesity; risk variants; obesity gene; gene risk ... See more keywords
Association of three single nucleotide polymorphisms in interleukin 6 gene with risk of chronic obstructive pulmonary disease.
Sign Up to like & getrecommendations! Published in 2022 at "Gene"
DOI: 10.1016/j.gene.2022.146467
Abstract: BACKGROUNDS Experimental studies have implicated the involvement of interleukin 6 (IL6) in chronic obstructive pulmonary disease (COPD), supporting the possible association between genetic alterations in IL6 gene and risk of COPD. OBJECTIVES We aimed to… read more here.
Keywords: gene risk; chronic obstructive; gene; obstructive pulmonary ... See more keywords
The genetic variations in SAP97 gene and the risk of schizophrenia in the Chinese Han population: a further study
Sign Up to like & getrecommendations! Published in 2020 at "Psychiatric Genetics"
DOI: 10.1097/ypg.0000000000000257
Abstract: Supplemental Digital Content is available in the text. Background and Methods Based on our previous discovery that SAP97 rs3915512 polymorphism significantly affects the cognitive function of schizophrenia, we further genotyped the other 12 single-nucleotide polymorphisms… read more here.
Keywords: genetic variations; gene risk; population; variations sap97 ... See more keywords
A Neural-Related Gene Risk Score for Head and Neck Squamous Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Oral diseases"
DOI: 10.1111/odi.14434
Abstract: OBJECTIVES This study aimed to establish a neural-related gene risk score (NRGRS) for the prediction of head and neck squamous cell carcinoma prognosis, and explore its predictive value on the benefit of immune checkpoint inhibitor… read more here.
Keywords: risk score; head neck; neural related; gene risk ... See more keywords
Identification of 8-gene risk prediction signature associated with NOTCH1 in stomach adenocarcinoma based on bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastrointestinal Oncology"
DOI: 10.21037/jgo-22-685
Abstract: Background Stomach adenocarcinoma (STAD), is the most common histological type of gastric cancer (GC) with high mortality and poor prognosis. We sought to investigate the contribution of Notch receptor 1 (NOTCH1) to STAD immunity. Methods… read more here.
Keywords: gene risk; risk prediction; value; receptor ... See more keywords
Identification of a Prognostic 3-Gene Risk Prediction Model for Thyroid Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2020.00510
Abstract: Objective: We aimed to screen the genes associated with thyroid cancer (THCA) prognosis, and construct a poly-gene risk prediction model for prognosis prediction and improvement. Methods: The HTSeq-Counts data of THCA were accessed from TCGA… read more here.
Keywords: risk; gene risk; analysis; model ... See more keywords